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Phosphine, diphenyl(2-phenylethyl)-, also known as triphenylphosphine, is a white solid chemical compound that is soluble in organic solvents. It is commonly used as a ligand in coordination chemistry and as a reagent in organic synthesis. Triphenylphosphine has a variety of applications in the pharmaceutical and agrochemical industries, as well as in the production of specialty chemicals. It is also used in the preparation of active pharmaceutical ingredients and in the manufacture of dyes and pigments. Known for its ability to facilitate a wide range of chemical reactions, triphenylphosphine is an important compound in the field of organic chemistry.

5952-49-8

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5952-49-8 Usage

Uses

Used in Pharmaceutical Industry:
Phosphine, diphenyl(2-phenylethyl)is used as a ligand in coordination chemistry for the development of new pharmaceutical compounds. Its ability to facilitate a wide range of chemical reactions makes it an important compound in the synthesis of active pharmaceutical ingredients.
Used in Agrochemical Industry:
Phosphine, diphenyl(2-phenylethyl)is used as a reagent in organic synthesis for the production of agrochemicals. Its versatility in facilitating chemical reactions contributes to the development of new and improved agrochemical products.
Used in Specialty Chemicals Production:
Phosphine, diphenyl(2-phenylethyl)is used as a reagent in the production of specialty chemicals. Its ability to facilitate a wide range of chemical reactions makes it an important compound in the synthesis of specialty chemicals.
Used in Dyes and Pigments Manufacturing:
Phosphine, diphenyl(2-phenylethyl)is used in the manufacture of dyes and pigments. Its role in facilitating chemical reactions contributes to the development of new and improved dyes and pigments for various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 5952-49-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,9,5 and 2 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 5952-49:
(6*5)+(5*9)+(4*5)+(3*2)+(2*4)+(1*9)=118
118 % 10 = 8
So 5952-49-8 is a valid CAS Registry Number.

5952-49-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name diphenyl(2-phenylethyl)phosphane

1.2 Other means of identification

Product number -
Other names Diphenyl-phenaethyl-phosphin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5952-49-8 SDS

5952-49-8Relevant academic research and scientific papers

Homoleptic Chiral Benzamidinate Complexes of the Heavier Alkaline Earth Metals and the Divalent Lanthanides

He, Meng,Gamer, Michael T.,Roesky, Peter W.

, p. 2638 - 2644 (2016)

Reaction of the chiral amidine N,N′-bis(1-phenylethyl)benzamidine ((S)-HPEBA), KCH(SiMe3)2, and MI2 (M = Ca, Sr, Ba) or LnI2 (Ln = Eu, Yb) in a 2:2:1 stoichiometric ratio resulted in the chiral homoleptic monome

Calcium complexes with imino-phosphinanilido chalcogenide ligands for heterofunctionalisation catalysis

Anga, Srinivas,Carpentier, Jean-Fran?ois,Panda, Tarun K.,Roisnel, Thierry,Sarazin, Yann

, p. 57835 - 57843 (2016)

The syntheses, characterisation and utilisation of the calcium complexes [{Lx}CaN(SiMe3)2·(THF)] supported by monoanionic, tridentate imino-phosphinanilido chalcogenide ligands {Ph2P(E)-N-C6H4/s

Potassium and well-defined neutral and cationic calcium fluoroalkoxide complexes: Structural features and reactivity

Roca, Sorin-Claudiu,Roisnel, Thierry,Dorcet, Vincent,Carpentier, Jean-Franois,Sarazin, Yann

, p. 5630 - 5642 (2014)

The fluorinated aminoether alcohols (1-aza-12-crown-4)CH2C(CF3)2OH ({RO1F}H), (MeOCH2CH2)2NCH2C(CF3)2OH ({RO2F}H

Bis(imino)carbazolate: A Master Key for Barium Chemistry

Carpentier, Jean-Fran?ois,Cartron, Julien,Chapple, Peter M.,Cordier, Marie,Dorcet, Vincent,Kahlal, Samia,Roisnel, Thierry,Saillard, Jean-Yves,Sarazin, Yann

, p. 9120 - 9126 (2020)

Reported here is a readily available bis(imino)carbazole-based proligand that constitutes a convenient entry point into the challenging synthetic molecular chemistry of barium. It enables the preparation of rare or even, up to now, unknown, solution-stabl

Nickel-catalyzed coupling of R2P(O)Me (R = aryl or alkoxy) with (hetero)arylmethyl alcohols

Li, Wei-Ze,Wang, Zhong-Xia

, p. 2233 - 2242 (2021/03/24)

α-Alkylation of methyldiarylphosphine oxides with (hetero)arylmethyl alcohols was performed under nickel catalysis. Various arylmethyl and heteroarylmethyl alcohols can be used in this transformation. A series of methyldiarylphosphine oxides were alkylated with 30-90% yields. Functional groups on the aromatic rings of methyldiarylphosphine oxides or arylmethyl alcohols including OMe, NMe2, SMe, CF3, Cl, and F groups can be tolerated. The conditions are also suitable for the α-alkylation reaction of dialkyl methylphosphonates.

A Commercially Available Ruthenium Compound for Catalytic Hydrophosphination

Cibuzar, Michael P.,Dannenberg, Steven G.,Waterman, Rory

, p. 446 - 451 (2019/08/26)

Hydrophosphination with a commercially available ruthenium compound, bis(cyclopentadienylruthenium dicarbonyl) dimer ([CpRu(CO)2]2), was explored. Styrene derivatives or Michael acceptors react readily with either primary or secondar

Ln(ii) amido complexes coordinated by ring-expanded N-heterocyclic carbenes-promising catalysts for olefin hydrophosphination

Lapshin, Ivan V.,Cherkasov, Anton V.,Asachenko, Andrey F.,Trifonov, Alexander A.

supporting information, p. 12913 - 12916 (2020/11/05)

First Ln(ii) ring-expanded NHC complexes (er-NHC)Ln[N(SiMe3)2]2 (Ln = Sm, Yb) are synthesized and proved to be highly efficient pre-catalysts for the intermolecular hydrophosphination of such indolent substrates as 1-alkenes, cyclohexene and norbornene. This journal is

A bench-stable copper photocatalyst for the rapid hydrophosphination of activated and unactivated alkenes

Dannenberg, Steven G.,Waterman, Rory

supporting information, p. 14219 - 14222 (2020/11/24)

Cu(acac)2 (1) is a highly active catalyst for the hydrophosphination of alkenes. Photocatalytic conditions are critical, and provide high conversions with unactivated substrates that have never before been reported with an air-stable catalyst or at ambient temperature. The commercial availability, ease of use, and broad substrate scope of compound 1 make hydrophosphination more available to synthetic chemists.

Hydrophosphination using [GeCl{N(SiMe3)2}3] as a pre-catalyst

Barrett,Sanderson,Mahon,Webster

supporting information, p. 13623 - 13626 (2020/11/17)

Transformations catalyzed by germanium are scarce, with examples mainly limited to widely catalyzed processes such as polymerisation of lactide and hydroboration of carbonyls. Reported is the first example of hydrophosphination using a germanium pre-catalyst, yielding anti-Markovnikov products when diphenylphosphine is reacted with styrenes or internal alkynes at room temperature. This journal is

Versatile Visible-Light-Driven Synthesis of Asymmetrical Phosphines and Phosphonium Salts

Arockiam, Percia Beatrice,Lennert, Ulrich,Graf, Christina,Rothfelder, Robin,Scott, Daniel J.,Fischer, Tillmann G.,Zeitler, Kirsten,Wolf, Robert

supporting information, p. 16374 - 16382 (2020/11/03)

Asymmetrically substituted tertiary phosphines and quaternary phosphonium salts are used extensively in applications throughout industry and academia. Despite their significance, classical methods to synthesize such compounds often demand either harsh reaction conditions, prefunctionalization of starting materials, highly sensitive organometallic reagents, or expensive transition-metal catalysts. Mild, practical methods thus remain elusive, despite being of great current interest. Herein, we describe a visible-light-driven method to form these products from secondary and primary phosphines. Using an inexpensive organic photocatalyst and blue-light irradiation, arylphosphines can be both alkylated and arylated using commercially available organohalides. In addition, the same organocatalyst can be used to transform white phosphorus (P4) directly into symmetrical aryl phosphines and phosphonium salts in a single reaction step, which has previously only been possible using precious metal catalysis.

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