59608-97-8

Usage

Uses

Used in Pharmaceutical Industry:
2-Amino-4-chloromethythiazole hydrochloride is utilized as a key intermediate in the synthesis of various drugs, playing a crucial role in the development of new medicinal compounds. Its unique chemical structure and properties make it a promising candidate for the creation of pharmaceuticals with diverse therapeutic applications.
Used in Medicinal Chemistry Research:
As a compound with potential biological activities, 2-Amino-4-chloromethythiazole hydrochloride is employed in medicinal chemistry research to explore its interactions with biological targets and its potential as a therapeutic agent. This research can lead to the discovery of new drugs and contribute to the advancement of medical treatments.

InChI:InChI=1/C4H5ClN2S/c5-1-3-2-8-4(6)7-3/h2H,1H2,(H2,6,7)

Upstream product

• 17356-08-0 thiourea 
• 534-07-6 1,3-Dichloroacetone 

Downstream Products

• 5198-77-6 2-bromo-4-chloromethyl-1,3-thiazole 
• 123685-72-3 2-amino-4-[4-(diphenylmethoxy)piperidinomethyl]thiazole 
• 1003584-27-7 1-(3-fluorobenzyl)-3-(4-(chloromethyl)thiazol-2-yl)urea 
• 1108653-16-2 1-(3,5-difluorobenzyl)-3-(4-chloromethylthiazol-2-yl) urea 
• 1173792-95-4 4-{[({(1-methyl-1H-tetrazol-5-yl)[4-methyl-3-(trifluoromethyl)phenyl]methylidene}amino)oxy]methyl}-1,3-thiazol-2-amine 
• 21679-21-0 thiosulfuric acid S-(2-amino-thiazol-4-ylmethyl) ester 
• 17386-09-3 4-pyrrolidin-1-ylmethyl-thiazol-2-ylamine 
• 116252-53-0 4-((dimethylamino)methyl)thiazole-2-amine 
• 51307-43-8 2-amino-4-hydroxymethylthiazole 
• 1603-91-4 4-methylthiazol-2-ylamine 
• 17386-11-7 4-azepan-1-ylmethyl-thiazol-2-ylamine 
• 7460-59-5 N-(4-(chloromethyl)thiazol-2-yl)acetamide 
• 220041-34-9 2-(2-aminothiazol-4-yl)acetonitrile 
• 1254558-78-5 2-(2-bromothiazol-4-yl)acetonitrile 

Relevant academic research and scientific papers

Structure-activity relationship studies of antiplasmodial aminomethylthiazoles

Structure-activity relationship (SAR) studies around a previously reported antimalarial aminomethylthiazole pyrazole carboxamide 1 are reported. Several analogues were synthesised and profiled for in vitro antiplasmodial activity against the drug-sensitiv

Oxime ether compound and application thereof

The invention discloses an oxime ether compound with a novel structure, the structure is shown as a general formula I, and the definition of each substituent group in the formula is shown in the specification. The compound shown in the general formula I h

N -substituted -2 - amino -4 - saccharin-substituted methylthiazole compound with bactericidal activity Preparation method and application

N -substituted -2 - amino -4 - saccharin-substituted methylthiazole compounds with bactericidal activity, a preparation method and an application thereof relate to the technical field of organic synthesis and agricultural chemicals. Experiments prove that

Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides

The parasitic trypanosomes Trypanosoma brucei and T. cruzi are responsible for significant human suffering in the form of human African trypanosomiasis (HAT) and Chagas disease. Drugs currently available to treat these neglected diseases leave much to be

NOVEL COMPOUND, ORGANIC CATION TRANSPORTER 3 DETECTION AGENT, AND ORGANIC CATION TRANSPORTER 3 ACTIVITY INHIBITOR

[Problem] The present invention addresses the problem of providing a novel compound. The present invention also addresses the problem of providing an OCT3 detection agent or an OCT3 activity inhibitor, which comprises the novel compound. [Solution] A compound represented by formula (A), a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate thereof. ????????R1-R2-R3-R4?????(A)

ANTIBACTERIAL SULFONE AND SULFOXIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS

The present invention provides novel sulfone and sulfoxide substituted heterocyclic urea compounds having useful antibacterial activity. Use of these compounds as pharmaceutical compositions and methods of production are provided.

ANTIBACTERIAL HETEROCYCLIC UREAS

The present invention provides novel heterocyclic urea compounds having useful antibacterial activity, pharmaceutical compositions comprising one or more of these compounds, methods of making the same, and methods of using the same.

RHO KINASE INHIBITORS

Substituted amide and urea derivatives useful as inhibitors of Rho kinase are described, which inhibitors can be useful in the treatment of various disorders such as cardiovascular diseases, cancer, neurological diseases, renal diseases, bronchial asthma, erectile dysfunction and glaucoma.

AMINE COMPOUNDS

The present invention provide a compound of the formula:wherein ring A represents an aromatic ring optionally having substituents; B, Y and Ya are the same or different and each represents a bond, etc.; R1 and R2 are the same or different and each represents a hydrogen atom, etc.; R3 represents a hydrogen atom, etc.; R4 and R5 are the same or different and each represents a hydrogen, etc.; R6 represents an indolyl group optionally having substituents; and Z and Za are the same or different and each represents a hydrogen atom, etc.; or a salt thereof or a prodrug thereof, having a somatostatin receptor binding inhibition activity and is useful for preventing and/or treating diseases associated with somatostatin.

ANTICANCER COMPOUNDS

This invention features compounds having formula (I): wherein, R1, R 2,R3, R4, R6, R7, T, X, and Y are as defined herein. This invention also features a method for treating cancer. The method includes administrating to a subject in need thereof a compound of formula (I).