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59847-20-0

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59847-20-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 59847-20-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,8,4 and 7 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 59847-20:
(7*5)+(6*9)+(5*8)+(4*4)+(3*7)+(2*2)+(1*0)=170
170 % 10 = 0
So 59847-20-0 is a valid CAS Registry Number.

59847-20-0Relevant articles and documents

Intramolecular Vinylation of Aryl Rings by Vinyl Cations

Fang, Jian,Brewer, Matthias

, p. 7384 - 7387 (2018)

A Lewis acid mediated intramolecular electrophilic vinylation of aryl rings by vinyl cations is reported. This reaction takes advantage of β-hydroxy-α-diazo ketones as vinyl cation precursors and provides good yields of tricyclic 1-indenones that contain

Discovery of 2-(1H-indazol-1-yl)-thiazole derivatives as selective EP 1 receptor antagonists for treatment of overactive bladder by core structure replacement

Atobe, Masakazu,Naganuma, Kenji,Kawanishi, Masashi,Morimoto, Akifumi,Kasahara, Ken-Ichi,Ohashi, Shigeki,Suzuki, Hiroko,Hayashi, Takahiko,Miyoshi, Shiro

, p. 1327 - 1333 (2014/03/21)

We have designed a series of potent EP1 receptor antagonists. These antagonists are a series of 2-(1H-indazol-1-yl)-thiazoles in which the core structure was replaced with pyrazole-phenyl groups. In preliminary conscious rat cystometry experiments, two representative candidates, 2 and 22, increased bladder capacity. In particular, the increase using 22 was approximately 2-fold that of the baseline. More detailed profiling of this compound and further optimization of this series promises to provide a novel class of drug for treating overactive bladder (OAB).

BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS

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Page/Page column 41, (2010/03/02)

A nitrogen-containing bicyclic heterocyclic compound represented by the following formula (1) is provided. When the compound or a salt thereof is administered to a human being or an animal, the compound has a strong antagonistic action against EP1 recepto

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