59853-92-8Relevant academic research and scientific papers
Potent and selective ketoamide-based inhibitors of cysteine protease, cathepsin K
Tavares, Francis X.,Deaton, David N.,Miller, Aaron B.,Miller, Larry R.,Wright, Lois L.,Zhou, Hui-Qiang
, p. 5049 - 5056 (2004)
Cathepsin K, a lysosomal cysteine protease of the papain superfamily, is abundantly and selectively expressed in osteoclasts, suggesting that this enzyme is crucial for bone resorption. Prevention of osteoclast-mediated bone resorption via inhibition of c
NOVEL CARBOXAMIDE DERIVATIVES AS HIV INHIBITORS
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Page/Page column 27, (2011/06/19)
The present invention relates to carboxamide derivatives of Formula (I), where B1, B2, X, L, n, R, R1, R2, Z1, Z2, Rx and Ry are as defined in the claims, as compounds and compositions for inhibiting Human Immunodeficiency Virus (HIV) and process for making the compounds.
