59908-54-2

Basic information

• Product Name: 5-METHOXY-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID
• Synonyms: 5-methoxy-1-methyl-2-indolecarboxylic acid;5-methoxy-1-methyl-indole-2-carboxylic acid;5-methoxy-1-methylindole-2-carboxylic acid;CHEMBRDG-BB 4002597;5-METHOXY-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID;AKOS JY2082871;TIMTEC-BB SBB011099;5-methoxy-1-methyl-1H-indole-2-carboxylic acid(SALTDATA: FREE)
• CAS NO: 59908-54-2
• Molecular Formula: C₁₁H₁₁NO₃
• Molecular Weight: 205.21
• Mol File: 59908-54-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 216 °C
• Boiling Point: 422.3 °C at 760 mmHg
• Flash Point: 209.2 °C
• Appearance: /
• Density: 1.26 g/cm³
• Vapor Pressure: 6.91E-08mmHg at 25°C
• Refractive Index: 1.588
• Storage Temp.: 2-8°C
• PKA: 4.10±0.30(Predicted)
• CAS DataBase Reference: 5-METHOXY-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHOXY-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID(59908-54-2)
• EPA Substance Registry System: 5-METHOXY-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID(59908-54-2)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 59908-54-2(Hazardous Substances Data)

Usage

General Description

5-Methoxy-1-methyl-1H-indole-2-carboxylic acid is a chemical compound with the formula C12H11NO3. It belongs to the class of organic compounds known as indoles, which are aromatic heterocyclic structures containing a benzene ring fused to a pyrrole ring. Being an indole derivative, it has several potential applications, including in pharmaceuticals and material science, though specific uses of this compound may vary. Its specific properties can also be attributed to its individual functional groups; the presence of a carboxylic acid group indicates it likely exhibits acidic properties.

InChI:InChI=1/C11H11NO3/c1-12-9-4-3-8(15-2)5-7(9)6-10(12)11(13)14/h3-6H,1-2H3,(H,13,14)

Upstream product

• 4382-54-1 5-methoxy-1H-indole-2-carboxylic acid 
• 940-11-4 N-methyl-N-nitroso-p-anisidine 
• 4792-58-9 ethyl 5-methoxy-1H-indole-2-carboxylate 
• 67929-87-7 5-methoxy-1-methyl-1H-indole-2-carboxylic acid methyl ester 
• 59908-56-4 Ethyl <(5-methoxy-1-methyl)indol-2-yl>carboxylate 
• 35292-54-7 N-methyl-N-(p-methoxyphenyl)hydrazine 
• 108-56-5 diethyl oxaloacetate 
• 127-17-3 2-oxo-propionic acid 

Downstream Products

• 160153-65-1 N-methyl-N-phenyl-5-(3-methoxymethyl)indole-2-carboxamide 
• 317374-53-1 C₁₈H₁₇N₃O₃ 
• 1048685-09-1 C₁₉H₂₀N₂O₄ 
• 13523-92-7 1-methyl-1H-indol-5-ol 
• 147729-01-9 N-benzyloxycarbonyl-N-methyl-2-(5-methoxy-1-methylindolyl)amine 
• 147729-00-8 N-benzyloxycarbonyl-2-(5-methoxy-1-methylindolyl)amine 

Relevant articles and documents

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From far west to east: Joining the molecular architecture of imidazole-like ligands in ho-1 complexes

HO-1 overexpression has been reported in several cases/types of human malignancies. Unfortunately, poor clinical outcomes are reported in most of these cases, and the inhibition of HO-1 is considered a valuable and proven anticancer approach. To identify

Novel indole-2-carboxamide and cycloalkeno[1,2-b]indole derivatives. Structure-activity relationships for high inhibition of human LDL peroxidation

Series of indole-2-carboxamide and cycloalkeno[1,2-b]indole derivatives were synthesized and evaluated in order to determine the necessary structural requirements for a high inhibition of human LDL copper-induced peroxidation. Various modulations were sys