60188-33-2

Usage

Uses

Used in Organic Solvent Applications:
2,3,7,8,12,13,17,18-Octaethyl-5-phenylporphyrine is used as a hydrophobic compound for applications in organic solvents, leveraging its high hydrophobicity to interact with and dissolve in non-polar solvents.
Used in Dye Development:
2,3,7,8,12,13,17,18-Octaethyl-5-phenylporphyrine is used as a precursor in the development of novel dyes, due to its porphyrin structure and light-absorbing properties, which are essential for creating dyes with specific color characteristics.
Used in Catalyst Development:
2,3,7,8,12,13,17,18-Octaethyl-5-phenylporphyrine is used as a component in the creation of new catalysts, where its ability to bind metal ions and its structural features can enhance the catalytic activity in various chemical reactions.
Used in Photodynamic Therapy Materials:
2,3,7,8,12,13,17,18-Octaethyl-5-phenylporphyrine is used as a potential material in photodynamic therapy, where its light-absorbing properties can be utilized to generate reactive oxygen species upon light exposure, which is crucial for the therapeutic effect in treating certain diseases.

Upstream product

• 2683-82-1 2,3,7,8,12,13,17,18-octaethyl-porphyrin 
• 591-51-5 phenyllithium 
• 100-52-7 benzaldehyde 
• 106-40-1 4-bromo-aniline 
• 10199-92-5 ethyl 5-acetoxylmethyl-3,4-diethylpyrrole-2-carboxylate 
• 65858-34-6 2,2'-methylenebis(3,4-diethylpyrrole) 
• 37730-56-6 diethyl 3,3',4,4'-tetraethyl-2,2'-methylenedipyrrole-5,5'-dicarboxylate 
• 16200-50-3 ethyl 3,4-diethyl-5-methylpyrrole-2-carboxylate 
• 16200-52-5 3,4-diethyl-1H-pyrrole 
• 159428-02-1 α-(Hydroxymethyl)-3,4-diethylpyrrole 

Downstream Products

• 62987-92-2 Zn(5-phenyloctaethylporphyrin-2H) 
• 330206-66-1 copper octaethyl-5-phenylporphyrin 
• 65858-42-6 2,3,7,8,12,13,17,18-octaethyl-5,15-diphenyl-21H,23H-porphyrin 

Relevant academic research and scientific papers

Influence of the structure of the organic moiety of copper(II) porphyrins on their reactivity toward acids

The acid-induced dissociation of copper(II) porphyrin complexes with a high degree of meso- and β-substitution in the ligand was studied. The copper(II) complexes with octaethylporphyrins containing 0, 1, 2, 3, and 4 meso-phenyl substituents were ranked with respect to the stability. Octaβ-alkyl and unsymmetrical meso-phenyl substitution affects not only the quantitative characteristics of dissociation of the complexes but also the kinetic relationships of the process. 2005 Pleiades Publishing, Inc.

The reaction of porphyrins with organolithium reagents

Porphyrins react readily with organolithium reagents, preferentially in the meso positions. The overall reaction is a nucleophilic substitution and proceeds via initial reaction of the organic nucleophile with a meso carbon yielding an anionic species whi

Highly substituted 2,3,7,8,12,13,17,18-octaethylporphyrins with meso aryl residues

Highly substituted porphyrin-bearing meso aryl groups are useful compounds for optical applications and for studies on the interrelationship between the substituent pattern, macrocycle conformation and physical properties. They serve as biomimetic models for the function of tetrapyrroles in nature and help to elucidate modulation of cofactor properties through conformational effects. Using a sequence of lithium organic substitution reactions the synthesis of novel free base 5,10-A2- and 5,10-AB-2,3,7,8,12,13,17,18-octaethylporphyrins bearing donating groups such as -OMe and -NMe2 on the aryl-substituent was achieved. Larger aromatic residues (1-naphthyl, 9-anthracenyl and 9-phenanthrenyl) could be introduced into the macrocycle system as well, and these systems were used for the preparation of highly substituted porphyrins with a mixed substituent pattern. Using phenanthrenyl derivatives, the complete series of meso phenanthrenyl substituted octaethylporphyrins was successfully synthesized and the palladium complexes were prepared for photophysical investigations. Structural studies clearly showed the influence of individual substituents on the conformation of the tetrapyrrole macrocycle and conformational analyses revealed the variation of the underlying distortion modes depending on the type and arrangement of the meso substituents.

Phenyl-substituted porphyrins. 1. Synthesis of meso-phenyl-substituted porphyrins

A method was developed for the synthesis of a series of meso-phenyl-substituted octaalkylporphyrins with various numbers of phenyl groups at various positions. Some of their properties were studied.

SNAr reactions of β-substituted porphyrins and the synthesis of meso substituted tetrabenzoporphyrins

Reaction of 2,3,7,8,12,13,17,18-octaethylporphyrin with LiR reagents containing functional groups readily yields meso substituted derivatives suitable for further transformations with residues such as -p-C 6H5Br, -p-C6Hsu

Kinetics of Complex Formation of Sterically Distorted Porphyrins with Copper Acetate in Pyridine and Dimethylformamide

The kinetics of complex formation of octaethylporphine, 5-monophenyloctaethylporphyrin, 5,15-diphenyloctaethylporphyrin, 5,10,15,20-tetraphenyloctaethylporphyrin, and dodecaphenylporphyrin with copper acetate in pyridine and dimethylformamide was studied.