604-95-5

Upstream product

• 17024-18-9 2-nitrophenanthrene 
• 84-11-7 9,10-phenanthrenequinone 
• 7697-37-2 nitric acid 
• 64-19-7 acetic acid 
• 85-01-8 phenanthrene 
• 1392143-84-8 4-nitro-[1,1'-biphenyl]-2,2'-dicarbaldehyde 
• 40138-16-7 2-formylbenzene boronic acid 
• 84459-32-5 2-bromo-5-nitrobenzaldehyde 

Downstream Products

• 36043-49-9 2-aminophenanthrene-9,10-dione 
• 7463-76-5 2-nitro-phenanthrene-9,10-dione dioxime 
• 7463-77-6 2-nitro-phenanthrene-9,10-dione-(Z,Z)-dioxime 
• 7647-01-0 hydrogenchloride 
• 5101-11-1 2-Nitro-9,10-bis-(N-benzyloxycarbonyl-glycyloxy)-phenanthren 
• 91693-19-5 6-Brom-2-nitro-fluoren-9-on 
• 4088-81-7 2-hydroxy-phenanthrene-9,10-dione 

Relevant academic research and scientific papers

Suzuki cross coupling followed by cross dehydrogenative coupling: An efficient one pot synthesis of Phenanthrenequinones and analogues

An efficient one pot protocol has been developed towards the synthesis of substituted phenanthrenequinone and analogous derivatives via Suzuki cross coupling followed by copper catalyzed cross dehydrogenative coupling.

COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING PTEN INHIBITORS

This invention is directed to, inter alia, compounds, methods, systems, and compositions for the maintenance, enhancement, and expansion of hematopoietic stem cells derived from sources of non-mobilized peripheral blood. Also provided herein are compounds of Formula I which are useful in maintaining, enhancing, and expanding of hematopoietic stem cells.

The first colorimetric receptor for the B4O72- anion based on nitro substituted phenanthroimidazole ferrocene derivatives

Four phenanthroimidazole ferrocene derivatives (2a-2d) were designed, synthesized and characterized by 1H NMR, 13C NMR and high-resolution mass spectroscopy (HRMS). Recognition of 12 anions by 2a-2d was investigated by UV-Vis absorption analysis, showing that 2b and 2d sensed B4O72- selectively among the tested anions with an obvious color change observed. 1H NMR titrations and theoretical calculations demonstrated that 2b binds B4O72- through O?H hydrogen bonding and O?B interactions between the nitro moiety and the B4O72- anion.

Cd45 inhibitors

Substituted phenanthrene-9,10-diones in accord with structural diagram I, 1compositions thereof and methods for the use thereof, for the treatment of T cell mediated conditions such as autoimmune diseases and organ graft rejection. In compounds of the invention, R1 at each occurrence is independently selected from hydrogen, halogen, NH-tosyl, N-di-tosyl, NH2, NO2, NH—CO—R2, CO—NH—R2, Ar, (CH2)nCH(COOH)R3 COR3 and NHCOCH2CH(COOH)NHR4, where R2, R3 and R4 are a selected from a variety of substituted or unsubstituted alkyl and aryl groupstand oligopeptides.

Process for the production of nitro derivatives of aromatic compounds

Nitroderivates of aromatic compounds which are difficult to nitrate, can readily be obtained by nitration providing that the aromatic compound is treated with nitric acid or another nitrating agent in the presence of aliphatic or cycloaliphatic hydrocarbons monosubstituted or polysubstituted by halogen, the nitro group or an alkyl sulphonyl group, and the nitro derivative formed subsequently isolated.