60483-07-0

Basic information

• Product Name: QUINOLIN-2-YLMETHYL ACETATE
• Synonyms: QUINOLIN-2-YLMETHYL ACETATE;2-Quinolinemethanol 2-acetate
• CAS NO: 60483-07-0
• Molecular Formula: C₁₂H₁₁NO₂
• Molecular Weight: 201.22
• Mol File: 60483-07-0.mol

Chemical Properties

• Boiling Point: 305.8°C at 760 mmHg
• Flash Point: 138.7°C
• Appearance: /
• Density: 1.186g/cm³
• Vapor Pressure: 0.000805mmHg at 25°C
• Refractive Index: 1.601
• CAS DataBase Reference: QUINOLIN-2-YLMETHYL ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: QUINOLIN-2-YLMETHYL ACETATE(60483-07-0)
• EPA Substance Registry System: QUINOLIN-2-YLMETHYL ACETATE(60483-07-0)

Safety Data

• Hazardous Substances Data: 60483-07-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H11NO2/c1-9(14)15-8-11-7-6-10-4-2-3-5-12(10)13-11/h2-7H,8H2,1H3

Upstream product

• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 65094-35-1 2-[(trimethylsilyl)methyl]quinoline 
• 1076-28-4 2-methylquinoline N-oxide 
• 67-66-3 chloroform 
• 75-36-5 acetyl chloride 
• 91-63-4 2-methylquinoline 

Downstream Products

• 91-63-4 2-methylquinoline 
• 1780-17-2 quinolin-2-ylmethanol 
• 13425-28-0 phenyl-carbamic acid-[2]quinolylmethyl ester 
• 4377-41-7 2-Chloromethylquinoline 

Relevant articles and documents

Metal-free C(sp3)–H oxidation of 2-methylquinolines with PIDA under microwave irradiation

An efficient metal-free protocol has been developed for the sp3C–H bond oxidation of 2-methylquinolines in the presence of PIDA under microwave irradiation, providing 2-quinolinecarboxaldehydes with moderate to high yields and excellent selectivities. A wide range of 2-quinolinecarboxaldehydes with different functional groups have been synthesized. A tentative mechanism has been presented to explain this highly selective oxidation process.

Oxidation of substituted pyridines PyrCHRSiMe3 (R=H, Me, Ph) and substituted quinolines QnCH2SiMe3 with hypervalent iodine reagents

Oxidation of a variety of substituted pyridines, PyrCHRSiMe3 (R = H, Me, Ph) and quinolines, QnCH2SiMe3 with hypervalent iodine reagents PIDA, (PhI(OCOCH3)2) and PIFA, (PhI(OCOCF3)2) has been studied. Oxy-desilylation with PIDA/TBAF gives low to moderate yields of PyrCHROR1 and QnCH2OR1 (R1 = H, Ac), while good yields of PyrCHROH and QnCH2OH are obtained when PIFA is used.