60561-60-6Relevant academic research and scientific papers
Strecker reactions with hexacyanoferrates as non-toxic cyanide sources
Grundke, Caroline,Opatz, Till
supporting information, p. 2362 - 2366 (2019/05/17)
The Strecker reaction is the most widely applied three-component reaction. Although highly useful for the preparation of α-amino nitriles, α-amino acids, hydantoins and numerous related compounds, the need for the application of toxic sources of HCN limits its application in both academic and industrial settings. Here, we present a facile protocol for Strecker reactions using a mixture of potassium ferri- and ferrocyanides as a non-toxic substitute.
A unique combination of KI/ZnFe2O4 as a catalyst for oxidative Strecker reaction
Ghandi, Leila,Kazemi Miraki, Maryam,Karimi, Meghdad,Radfar, Iman,Heydari, Akbar
, (2018/11/23)
α-Aminonitriles as key intermediates for the preparation of α-amino acid derivatives, amides, diamines, peptides, proteins and heterocycles were synthesized through methylarene oxidation in the Strecker reaction using a unique combination of KI/ZnFe2O4 as the best catalyst and aqueous tert-butyl hydroperoxide as oxidant. A wide range of amines and methylarenes were converted to the corresponding products. Operational simplicity, short reaction time and recyclability of the catalyst are advantages of this protocol.
Alpha-cyanidation method of mono-alkyl substituted aniline
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Paragraph 0023; 0024; 0114; 0115; 0116; 0117, (2017/09/13)
The invention discloses an alpha-cyanidation method of mono-alkyl substituted aniline. According to the method, various aromatic, aliphatic, and heterocycle substituted secondary amines of anilines are taken as the raw materials, trimethylsilyl cyanide is
Dehydroascorbic acid (DHAA) capped magnetite nanoparticles as an efficient magnetic organocatalyst for the one-pot synthesis of α-aminonitriles and α-aminophosphonates This article is dedicated to memory of Majid Shahriari
Saberi, Dariush,Cheraghi, Samaneh,Mahdudi, Samaneh,Akbari, Jafar,Heydari, Akbar
, p. 6403 - 6406 (2013/11/19)
A dehydroascorbic acid capped magnetite (DHAA-Fe3O4) catalyst is prepared and used for the one-pot synthesis of α-aminonitriles and α-aminophosphonates. Different derivatives of these compounds are synthesized in good yields.
