6061-13-8

Basic information

• Product Name: L-Aspartic acid, 3-methyl-, (3S)-
• CAS NO: 6061-13-8
• Molecular Formula: C5H9NO4
• Molecular Weight: 147.131
• Mol File: 6061-13-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: L-Aspartic acid, 3-methyl-, (3S)-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Aspartic acid, 3-methyl-, (3S)-(6061-13-8)
• EPA Substance Registry System: L-Aspartic acid, 3-methyl-, (3S)-(6061-13-8)

Safety Data

• Hazardous Substances Data: 6061-13-8(Hazardous Substances Data)

Upstream product

• 20268-80-8 diethyl 2-amino-3-methylsuccinate 
• 535-11-5 Ethyl 2-bromopropionate 
• 1068-90-2 2-acetylaminomalonic acid diethyl ester 
• 759-65-9 diethyl oxalpropionate 
• 90877-70-6 ethyl 2-acetamido-2-cyanoacetate 

Downstream Products

• 498-24-8 Mesaconic acid 
• 13398-41-9 (2S, 3S)-threo-β-methylmalic acid 
• 78433-58-6 ((1R,2R)-3-Benzyloxy-1-ethyl-2-methyl-propoxy)-tert-butyl-dimethyl-silane 
• 78433-60-0 (2R,3R)-3-((tert-butyldimethylsilyl)oxy)-2-methylpentyl 4-methylbenzenesulfonate 
• 72522-40-8 (4RS,6R,7R)-threo-serricornin 
• 115527-73-6 α-methyl (2S,3S)-N-trifluoroacetyl-3-methylaspartyl-m-chlorobenzoyl peroxide 
• 86535-06-0 (2R,3S)-threo-3-methylbutane-1,2,3-triol 4-benzyl ether 1-tosylate 
• 86562-36-9 (2R,3R)-threo-2-methylpentane-1,3-diol 3-THP ether 1-tosylate 
• 86535-10-6 (2S,3S)-threo-2-methylpentane-1,3-diol 3-THP ether 1-tosylate 
• 86535-18-4 2-methyl-3-pentanol (S)-(-)-MTPA ester 
• 86535-19-5 2-methyl-3-pentanol (R)-(+)-MTPA ester 
• 86535-17-3 (2R,3R)-threo-2-methylpentane-1,3-diol 1-tosylate 
• 86535-14-0 (2S,3S)-2-methyl-1-(4-methylbenzenesulfonyloxy)-3-pentanol 
• 86535-08-2 (2S,3S)-threo-2-methylpentane-1,3-diol 1-benzyl ether 3-THP ether 

Relevant articles and documents

Structures and Biosynthetic Pathway of Coprisamides C and D, 2-Alkenylcinnamic Acid-Containing Peptides from the Gut Bacterium of the Carrion Beetle Silpha perforata

Coprisamides C and D (1 and 2) were isolated from a gut bacterium, Micromonospora sp. UTJ3, of the carrion beetle Silpha perforata. Based on the combined analysis of UV, MS, and NMR spectral data, the planar structures of 1 and 2 were elucidated to be unreported derivatives of coprisamides A and B, cyclic depsipeptides bearing a 2-alkenylcinnamic acid unit and the unusual amino acids β-methylaspartic acid and 2,3-diaminopropanoic acid. The absolute configuration of 1 was determined using the advanced Marfey's method, phenylglycine methyl ester derivatization, and J-based configuration analysis. The biosynthetic gene clusters for the coprisamides were investigated based on genomic data from coprisamide-producing strains Micromonospora sp. UTJ3 and Streptomyces sp. SNU533. Coprisamide C (1) was active against the Mycobacterium tuberculosis mc26230 strain.

Organocatalytic synthesis of β-alkylaspartates via β-lactone ring opening

(Chemical Equation Presented) Cinchona alkaloid-catalyzed reaction of ethyl glyoxylate with substituted ketenes, formed in situ, gives disubstituted β-lactones in moderate yield and high enantiomeric excess. Subsequent azide ring opening, reduction, and e

SYNTHESIS AND ABSOLUTE STEREOCHEMISTRY OF SERRICORNIN

The absolute stereochemistry of serricornin (4,6-dimethyl-7-hydroxy-3-nonanone) was established as 4S, 6S, 7S by synthesizing both (4S, 6S, 7S)-isomer and its antipode.Only the natural enantiomer was bioactive.by