6067-45-4

Basic information

• Product Name: Bis(4-nitrophenyl) diketone
• Synonyms: 1,2-Bis(4-nitrophenyl)ethane-1,2-dione;4,4'-Dinitrobenzil;Bis(4-nitrophenyl) diketone;1,2-bis(4-nitrophenyl)-1,2-Ethanedione
• CAS NO: 6067-45-4
• Molecular Formula: C₁₄H₈N₂O₆
• Molecular Weight: 300.22
• Mol File: 6067-45-4.mol

Chemical Properties

• Melting Point: 213 °C
• Boiling Point: 532.3±35.0 °C(Predicted)
• Appearance: /
• Density: 1.471±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Bis(4-nitrophenyl) diketone(CAS DataBase Reference)
• NIST Chemistry Reference: Bis(4-nitrophenyl) diketone(6067-45-4)
• EPA Substance Registry System: Bis(4-nitrophenyl) diketone(6067-45-4)

Safety Data

• Hazardous Substances Data: 6067-45-4(Hazardous Substances Data)

Usage

Uses

Due to the limited information available on the specific applications of Bis(4-nitrophenyl) diketone, it is difficult to provide a comprehensive list of its uses. However, based on its chemical properties, it can be inferred that it may have potential applications in the following areas:
Used in Chemical Synthesis:
Bis(4-nitrophenyl) diketone is used as a reagent for the synthesis of various organic compounds. Its ability to react with other substances makes it a valuable component in the creation of new chemical entities.
Used in Research and Development:
Bis(4-nitrophenyl) diketone is used as a research compound for studying its reactivity and potential applications in different fields. Its unique structure and properties may lead to new discoveries and innovations.
Used in Material Science:
Bis(4-nitrophenyl) diketone is used as a precursor in the development of new materials with specific properties. Its potential to act as a hydrogen acceptor could be utilized in the creation of materials with tailored characteristics.

Upstream product

• 492-70-6 1,2-diphenyl-1,2-ethanediol 
• 7697-37-2 nitric acid 
• 2735-14-0 1,2-bis(4-nitrophenyl)acetylene 
• 636-98-6 p-nitrobenzene iodide 
• 937-31-5 (4-Nitrophenyl)acetylene 
• 17763-80-3 para-nitrophenyl triflate 
• 122-04-3 4-nitro-benzoyl chloride 
• 619-93-2 (Z)-4,4'-dinitrostilbene 
• 5466-94-4 4-Nitro-N-phenyl-benzimidoyl chloride 
• 555-16-8 4-nitrobenzaldehdye 
• 14224-99-8 2-methyl-4,5-diphenyloxazole 
• 51130-02-0 2-benzoyloxy-2-(4-nitrophenyl)acetonitrile 
• 13295-04-0 1.2-bis(4-nitrophenyl)ethane-1,2-diol 
• 102034-64-0 2-benzoyloxy-1,2-bis(4-nitrophenyl)ethanone 

Downstream Products

• 855293-17-3 4,4'-diamino-benzoin 
• 29602-15-1 4,4'-diaminobenzil 
• 62-23-7 4-nitro-benzoic acid 
• 621-95-4 4,4'-diaminodihydrostilbene 
• 852107-91-6 C₂₄H₁₇N₅O₄ 
• 852108-08-8 C₂₃H₁₄BrN₅O₄ 
• 43084-63-5 4,4'-dinitrobenzil dioxime 
• 21501-14-4 4,4-bis(acetylamino)benzil 
• 2810-93-7 4,4'-quinoxaline-2,3-diyl-bis-aniline 
• 85291-33-4 3-Hydroxy-2-methyl-3,4-bis-(4-nitro-phenyl)-4-oxo-butyric acid methyl ester 
• 514197-13-8 2,3-bis(4-aminophenyl)quinoxaline-6-carboxylic acid 
• 870119-73-6 4,5-bis-(4-nitro-phenyl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine 
• 870120-03-9 3-chloro-5,6-bis(p-nitrophenyl)pyridazine-4-carbonitrile 
• 870119-97-4 5,6-bis(4-nitrophenyl)-3-oxo-2,3-dihydropyridazine-4-carbonitrile 

Relevant articles and documents

Sequentially Pd/Cu-Catalyzed Alkynylation-Oxidation Synthesis of 1,2-Diketones and Consecutive One-Pot Generation of Quinoxalines

We report a simple and efficient one-pot synthesis of 1,2-diketones by concatenation of two Pd/Cu-catalyzed processes: Pd0/CuI-catalyzed Sonogashira coupling of terminal alkynes with aryl (pseudo)halides furnishes internal alkynes, which are directly transformed by PdII/CuII-catalyzed Wacker-type oxidation with DMSO and oxygen as dual oxidants to furnish 1,2-diketones. With this efficient, catalyst economical process, various aryl iodides and triflates are efficiently transformed in high yields into symmetrically and unsymmetrically substituted 1,2-diketones with various functional groups. This process can be readily extended to a consecutive one-pot synthesis of quinoxalines in a diversity-oriented fashion.

Rate Enhancement in CAN-Promoted Pd(PPh3)2Cl2-Catalyzed Oxidative Cyclization: Synthesis of 2-Ketofuran-4-carboxylate Esters

Stoichiometric ceric ammonium nitrate (CAN) and a catalytic amount of Pd(PPh3)2Cl2 (5 mol %) can rapidly produce multisubstituted 2-ketofuran-4-carboxylate esters from 2-propargylic 1,3-ketoesters via oxidative O-cyclization reaction. Pd(PPh3)2Cl2 was found to be the crucial catalyst as its inclusion greatly enhanced the rate of the reaction and cleanly afforded the products within minutes. Over 30 substrates were successfully converted to the desired compounds in mostly moderate to good yields.

Synthesis of smart bimetallic nano-Cu/Ag@SiO2 for clean oxidation of alcohols

Here, we have demonstrated the synthesis and characterization of silica supported bimetallic copper/silver nanoparticles (Cu/Ag@SiO2 NPs) and their application in the clean oxidation of benzoins/benzyl alcohols in the presence of tert-butyl hydroperoxide as a mild oxidant. All the reactions were very fast (4 h) and high yielding (95-99%), and the Cu/Ag@SiO2 NPs were very stable under the reaction conditions. The catalyst was recovered simply by filtration and reused eight times without loss of its catalytic performance.

Preparation method and antineoplastic activity of novel ruthenium complex containing 4,4'-dibromo-2,2'-dipyridyl

The invention provides a preparation method and antineoplastic activity of a novel ruthenium complex containing 4,4'-dibromo-2,2'-dipyridyl. The preparation method is characterized by comprising the following steps that 1, 4-nitrobenzaldehyde and vitamin

O-Benzoyl pyridine aldoxime and amidoxime derivatives: Novel efficient DNA photo-cleavage agents

O-Benzoyl derivatives of meta-, ortho- and para-pyridine aldoximes and amidoximes are novel efficient DNA photo-cleavage agents. In particular O-p-nitro-benzoyl derivatives 4, 8 and 15 were effective at concentrations as low as 1 μM. Both aldoximes and amidoximes were active under aerobic and anaerobic conditions, with a double-stranded to single-stranded DNA cleavage ratio of up to 1. These results give prospects for multiple applications, including phototherapeutic treatment of solid tumors. This journal is

C-H oxidation using graphite oxide

Graphite oxide was found to be an effective oxidant for use in a broad range of reactions, including the oxidation of olefins to their respective diones, methyl benzenes to their respective aldehydes, diarylmethanes to their respective ketones, and various dehydrogenations. The temperatures used in the reactions were typically mild (100-120 °C), and the heterogeneous nature of the oxidant facilitated isolation and purification of the desired products. In most cases, no by-products were observed and the desired products were isolated in good to excellent yields.

CARBOCATALYSTS FOR CHEMICAL TRANSFORMATIONS

The disclosure relates to catalytically active carbocatalysts, e.g., a graphene oxide or graphite oxide catalyst suitable for use in a variety of chemical transformations. In one embodiment, it relates to a method of catalyzing a chemical reaction of an organic molecule by reacting the organic molecule in the presence of a sufficient amount of graphene oxide or graphite oxide for a time and at a temperature sufficient to allow catalysis of a chemical reaction. According to other embodiments, the reaction may be an oxidation reaction, a hydration reaction, a dehydrogenation reaction, a condensation reaction, or a polymerization reaction. Some reactions may include auto-tandem reactions. The disclosure further provides reaction mixtures containing an organic molecule and graphene oxide or graphite oxide in an amount sufficient to catalyze a reaction of the organic molecule.

Novel one-pot procedure for the synthesis of 1,2-diketones

A simple and convenient one-pot procedure is reported for the synthesis of 1,2-diketones from corresponding benzoin-type condensation reaction of aromatic aldehydes in water with N,N-dialkylbenzimidazolium salt as condensation catalyst and ferric chloride as oxidizing reagent. Copyright Taylor & Francis Group, LLC.

Ruthenium catalyzed oxidation of 1,2-diols to 1,2-diketones using bromamine-T as an oxidizing agent

A variety of 1,2-diols were selectively oxidized to their corresponding 1,2-diketones with bromamine-T using RuCl3 · xH2O as catalyst in alkaline acetonitrile/ water (1:1) medium. The reaction was pH dependent (pH 8.4), and at higher pH the rate of the reaction decreased significantly. Copyright Taylor & Francis, Inc.

Combination therapy

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