13295-04-0

Basic information

• Product Name: 1,2-Ethanediol, 1,2-bis(4-nitrophenyl)-
• CAS NO: 13295-04-0
• Molecular Formula: C14H12N2O6
• Molecular Weight: 304.259
• Mol File: 13295-04-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1,2-Ethanediol, 1,2-bis(4-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Ethanediol, 1,2-bis(4-nitrophenyl)-(13295-04-0)
• EPA Substance Registry System: 1,2-Ethanediol, 1,2-bis(4-nitrophenyl)-(13295-04-0)

Safety Data

• Hazardous Substances Data: 13295-04-0(Hazardous Substances Data)

Upstream product

• 7664-93-9 sulfuric acid 
• 64-19-7 acetic acid 
• 14688-37-0 cis-p,p'-dinitrostilbene oxide 
• 36898-62-1 4,4'-dinitrobenzoin 
• 100-14-1 4-nitrobenzyl chloride 
• 30747-39-8 α,α'-bisacetoxy-p,p'-dinitrobibenzyl 
• 619-93-2 4,4'-dinitro stilbene 
• 968-01-4 (2SR,3SR)-2,3-bis(4-nitrophenyl)oxirane 
• 555-16-8 4-nitrobenzaldehdye 
• 3682-07-3 1,2-diacetoxy-1,2-diphenylethane 

Downstream Products

• 123371-45-9 ethyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate 
• 555-16-8 4-nitrobenzaldehdye 
• 3357-14-0 3,3,6,6-tetramethyl-9-(4-nitrophenyl)-1,8-dioxodecahydroacridine 
• 100063-71-6 Phosphoric acid mono-[2-hydroxy-1,2-bis-(4-nitro-phenyl)-ethyl] ester; compound with cyclohexylamine 
• 30747-39-8 α,α'-bisacetoxy-p,p'-dinitrobibenzyl 
• 97104-19-3 Ammonium 4,4'-dinitrohydrobenzoin-cyclophosphat 
• 5496-39-9 2-(4-nitrophenyl)-4,5-diphenyl-1H-imidazole 
• 6067-45-4 4,4'-dinitrobenzil 

Relevant articles and documents

SOME ORGANIC REACTIONS PROMOTED BY SAMARIUM DIIODIDE

Various homoallylic alcohols and homobenzylic alcohols were prepared by the reaction between aldehydes and allylic or benzylic halides in the presence of samarium diiodide.This iodide is also a very good reagent for formation of pinacols from aldehydes or ketones.The reactions are especially fast and selective in the case of substituted benzaldehydes.The reactivities of various nitrogen functional groups (imine, oxime, nitro, azo, cyano) towards SmI2 were also examined.

Biginelli reaction of vicinal diols: A new route for one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives

Background: 3,4-Dihydropyrimidin-2(1H)-one derivatives are an important class of nitrogen heterocycles. These compounds present a wide range of biological activities viz antibacterial, antifungal, and antidiabetic. Although many synthetic methods are available in the literature for the synthesis of these molecules, many of these methods have their own limitations such as use of excess of expensive catalyst and poor yields. Methods: The synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives is developed through the reaction of 1,2-diols, ethyl acetoacetate and urea in the presence of lead tetraacetate in dry ethanol under reflux conditions. Results: A series of 3,4-dihydropyrimidin-2(1H)-one derivatives were synthesized in good yields (82-95%) under reflux for 2-3.5 hours in ethanol solvent. The structural assignments of these compounds were made on the basis of elemental analysis and spectroscopic data. Conclusion: This protocol is an alternative to existing procedure for the synthesis of Biginelli compounds. The present methodology reduces the number of steps in total synthesis.

Pinacol coupling of aromatic aldehydes and ketones using magnesium in aqueous ammonium chloride under ultrasound

The pinacol coupling reaction of aromatic aldehydes and ketones was performed in 8-95% yield with magnesium in 0.1 M aqueous NH4C1 under ultrasound irradiation at r.t. for 3 h.