60693-37-0

Upstream product

• 199461-14-8 N-(4-fluorophenyl)succinamic acid 
• 108-30-5 succinic acid anhydride 
• 371-40-4 4-fluoroaniline 
• 6633-22-3 N-(4-fluorophenyl)maleimide 
• 757248-79-6 5-cyanoacetyl-1-(4-fluorophenyl)pyrrolidin-2-one 
• 297183-18-7 methyl N-(4-fluorophenyl)pyroglutamate 
• 757248-57-0 1-(4-fluorophenyl)-5-(2-methyl-2H-1,2,3-triazol-4-ylcarbonyl)pyrrolidin-2-one 
• 757248-56-9 1-(4-fluorophenyl)-4-[1,2,3-triazol-4⁽⁵⁾-ylcarbonyl]pyrrolidin-2-one 
• 757248-81-0 1-(4-fluorophenyl)-5-(tetrazol-5-ylacetyl)pyrrolidin-2-one 

Downstream Products

• 1263797-00-7 C₂₄H₂₅FN₄O₂S 
• 1263797-07-4 C₂₀H₁₇FN₄O₂S₂ 

Relevant academic research and scientific papers

Photoredox/Cobalt-Catalyzed C(sp3)-H Bond Functionalization toward Phenanthrene Skeletons with Hydrogen Evolution

The first example of photoredox strategy for synthesis of phenanthrene skeletons through C(sp3)-H functionalization under external oxidant-free conditions is achieved. This transformation relies on the keto-enol tautomerism of 1,3 dicarbonyl moiety, i.e., the enol form of 1,3-dicarbonyl derivatives with relatively lower oxidation potential can be activated by the excited acridinium photocatalyst. The electron and proton eliminated from the substrate are immediately captured by a cobaloxime catalyst to exclusively afford a-carbonyl radical for highly substituted 10-phenanthrenols in good to excellent yields.

Synthesis of 3-(5-amino-1: H -1,2,4-triazol-3-yl)propanamides and their tautomerism

Two complementary pathways for the preparation of N-substituted 3-(5-amino-1H-1,2,4-triazol-3-yl)propanamides (5) were proposed and successfully realized in the synthesis of 20 representative examples. These methods use the same types of starting material

Radical-mediated dehydrative preparation of cyclic imides using (NH4)2S2O8-DMSO: Application to the synthesis of vernakalant

Ammonium persulfate-dimethyl sulfoxide (APS-DMSO) has been developed as an efficient and new dehydrating reagent for a convenient one-pot process for the synthesis of miscellaneous cyclic imides in high yields starting from readily available primary amines and cyclic anhydrides. A plausible radical mechanism involving DMSO has been proposed. The application of this facile one-pot imide forming process has been demonstrated for a practical synthesis of vernakalant.

Substituent chemical shifts of N-arylsuccinanilic acids, N-arylsuccinimides, N-arylmaleanilic acids, and N-arylmaleimides

NMR spectra of a series of N-arylsuccinanilic acids, N-arylsuccinimides, N-arylmaleanilic acids, and N-arylmaleimides were examined to estimate the electronic effect of the amide and imide groups on the chemical shifts of the hydrogen and carbon nuclei of the benzene ring.