60982-72-1

Usage

Chemical class

Benzyl halides

Physical appearance

Colorless to pale yellow liquid

Odor

Pungent

Synthesis

Formed by the reaction of hexylbenzene with bromine

Uses

Reagent in organic synthesis, precursor in production of organic compounds, pharmaceutical industry, agrochemical industry, material science industry, manufacture of fragrances and flavoring compounds

Upstream product

• 623-24-5 1,4-bis(bromomethyl)benzene 
• 693-25-4 n-pentylmagnesium bromide 
• 21643-38-9 4-hexylbenzoic acid 
• 199786-54-4 (4-Hexyl-phenyl)-trimethyl-silane 
• 111-25-1 1-bromo-hexane 
• 118578-88-4 4-hexylphenylmethyl alcohol 
• 6999-03-7 1-bromo-4-(trimethylsilyl)benzene 
• 62150-34-9 1-n-hexyl-4-iodobenzene 
• 49763-69-1 4-hexylbenzaldehyde 

Downstream Products

• 118578-90-8 diethyl p-n-hexylbenzylphosphonate 
• 199786-55-5 2,5-dibromo-4-hexylbenzyl bromide 
• 1427308-29-9 tert-butyl 2,2-dimethyl-5-(4-(4-hexylbenzyl)phenethyl)-1,3-dioxan-5-ylcarbamate 
• 1352441-98-5 1,1-dicyano-2-methyl-4-(4-hexylphenyl)-1-butene 

Relevant academic research and scientific papers

Odorless substitutes for foul-smelling thiols: Syntheses and applications

Several alkanethiols and p-alkylphenylmethanethiols were synthesized, and their odors were compared with those of ethanethiol and benzyl mercaptan by human and instrumental sensors. Among the various thiols analyzed, 1-dodecanethiol (1) and p-heptylphenylmethanethiol (3) were revealed to be odorless. 1-Dodecanethiol (1) has been used instead of ethanethiol for dealkylation of ethers, and p-heptylphenylmethanethiol (3) can replace benzyl mercaptan in the preparation of a 1,3-mercapto alcohol from an α,β-unsaturated ketone. These odorless thiols will greatly improve the physical environment of the researcher working with these foul-smelling compounds.

Functionalized AB-type monomers for Suzuki polycondensation

A high yield synthesis of two phenylene and biphenylene derived AB-type monomers for Suzuki polycondensation is described. They carry solubilizing alkyl groups and free and methyl-protected hydroxy functional groups for further modifications.

Negative inotropic activity of para-substituted diethyl benzylphosphonates related to fostedil

Several para-substituted diethyl benzylphosphonates related to the calcium antagonist diethyl 4-(2-benzothiazolyl)benzylphosphonate (fostedil) have been studied.They produce a dose-dependent negative inotropic effect on left atrial muscle isolated from guinea pig heart.Some of the compounds are equipotent or slightly more potent than fostedil and diltiazem taken as reference drugs.Structure-activity relationships are discussed.Keywords: calcium antagonists / p-substituted diethyl benzylphosphonates / cardiodepressant activity