610-20-8 Usage
Description
2,3-bis(nitrooxy)succinic acid, commonly known as Angeli's salt, is a chemical compound with the molecular formula C6H6N2O10. It is recognized as a potent nitric oxide donor, which is significant in biomedical research due to its potential therapeutic effects. Angeli's salt is particularly noted for its impact on cardiovascular and pulmonary health, making it a subject of interest for medical and biotechnological applications.
Uses
Used in Cardiovascular Applications:
2,3-bis(nitrooxy)succinic acid is used as a vasorelaxant agent for inducing vasorelaxation and lowering blood pressure. Its application is based on the compound's ability to donate nitric oxide, which aids in the treatment of hypertension and other cardiovascular conditions by improving blood flow and reducing the workload on the heart.
Used in Pulmonary Applications:
In the field of pulmonary medicine, 2,3-bis(nitrooxy)succinic acid is utilized for its potential to alleviate conditions related to lung function. The release of nitric oxide can help in managing pulmonary diseases by promoting better lung function and reducing inflammation.
Used in Anti-inflammatory Applications:
2,3-bis(nitrooxy)succinic acid is used as an anti-inflammatory agent due to its demonstrated ability to reduce inflammation. This property makes it a candidate for the treatment of various inflammatory diseases where controlling inflammation is crucial for managing symptoms and preventing tissue damage.
Used in Antioxidant Applications:
As an antioxidant, 2,3-bis(nitrooxy)succinic acid is employed to neutralize harmful free radicals in the body. Its antioxidant properties suggest potential use in conditions where oxidative stress contributes to disease progression, thereby offering a protective role in maintaining cellular health.
Used in Biomedical Research:
In the realm of biomedical research, 2,3-bis(nitrooxy)succinic acid serves as a valuable tool for studying the role of nitric oxide in physiological and pathological processes. Its strong nitric oxide donating capability makes it an ideal compound for investigating the effects of nitric oxide on various biological systems and potential therapeutic targets.
Check Digit Verification of cas no
The CAS Registry Mumber 610-20-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,1 and 0 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 610-20:
(5*6)+(4*1)+(3*0)+(2*2)+(1*0)=38
38 % 10 = 8
So 610-20-8 is a valid CAS Registry Number.
InChI:InChI=1/C4H4N2O10/c7-3(8)1(15-5(11)12)2(4(9)10)16-6(13)14/h1-2H,(H,7,8)(H,9,10)
610-20-8Relevant articles and documents
An improved synthesis of 2-n-(propyl)-1H-imidazole-4,5-dicarboxylic acid diethyl ester
Wen, Xinmin,Yu, Xinhong,Tang, Jan
, p. 410 - 412 (2007/10/03)
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Design, Synthesis, Antineoplastic Activity, and Chemical Properties of Bis(carbamate) Derivatives of 4,5-Bis(hydroxymethyl)imidazole
Anderson, Wayne K.,Bhattacharjee, Debkumar,Houston, D. Michael
, p. 119 - 127 (2007/10/02)
A series of bis(carbamate) derivatives of 1,2-substituted 4,5-bis(hydroxymethyl)imidazoles were prepared and evaluated against murine P388 lymphocytic leukemia.Electron-withdrawing substituents at either N-1 or C-2 gave rise to inactive compounds.However, electron-donating substituents gave active compounds and the 2-(methylthio)-1-methyl derivative 2i (carmethizole), as the bis(N-methylcarbamate), was found to be very active.The derivative 2i, referred to by the name carmethizole, was also shown to be active against the MX-1 mammary xenograft, the human amelanotic melanoma cell line (LOX) xenograft, the M5076 sarcoma, and L1210 lymphocytic leukemia.The solution stability, water solubility, pKa, and log P of carmethizole are also reported.
