610-20-8 Usage
General Description
2,3-bis(nitrooxy)succinic acid, also known as Angeli's salt, is a chemical compound with the molecular formula C6H6N2O10. It is a strong nitric oxide donor and is used in biomedical research for its potential therapeutic effects, particularly in cardiovascular and pulmonary diseases. Angeli's salt has been shown to induce vasorelaxation and lower blood pressure in animal studies, making it a promising candidate for the treatment of hypertension and other cardiovascular conditions. Additionally, it has demonstrated anti-inflammatory and antioxidant properties, suggesting potential applications in the treatment of various inflammatory diseases. Overall, 2,3-bis(nitrooxy)succinic acid shows promise as a versatile and effective therapeutic agent in the field of medicine and biotechnology.
Check Digit Verification of cas no
The CAS Registry Mumber 610-20-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,1 and 0 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 610-20:
(5*6)+(4*1)+(3*0)+(2*2)+(1*0)=38
38 % 10 = 8
So 610-20-8 is a valid CAS Registry Number.
InChI:InChI=1/C4H4N2O10/c7-3(8)1(15-5(11)12)2(4(9)10)16-6(13)14/h1-2H,(H,7,8)(H,9,10)
610-20-8Relevant articles and documents
An improved synthesis of 2-n-(propyl)-1H-imidazole-4,5-dicarboxylic acid diethyl ester
Wen, Xinmin,Yu, Xinhong,Tang, Jan
, p. 410 - 412 (2007/10/03)
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Design, Synthesis, Antineoplastic Activity, and Chemical Properties of Bis(carbamate) Derivatives of 4,5-Bis(hydroxymethyl)imidazole
Anderson, Wayne K.,Bhattacharjee, Debkumar,Houston, D. Michael
, p. 119 - 127 (2007/10/02)
A series of bis(carbamate) derivatives of 1,2-substituted 4,5-bis(hydroxymethyl)imidazoles were prepared and evaluated against murine P388 lymphocytic leukemia.Electron-withdrawing substituents at either N-1 or C-2 gave rise to inactive compounds.However, electron-donating substituents gave active compounds and the 2-(methylthio)-1-methyl derivative 2i (carmethizole), as the bis(N-methylcarbamate), was found to be very active.The derivative 2i, referred to by the name carmethizole, was also shown to be active against the MX-1 mammary xenograft, the human amelanotic melanoma cell line (LOX) xenograft, the M5076 sarcoma, and L1210 lymphocytic leukemia.The solution stability, water solubility, pKa, and log P of carmethizole are also reported.
