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(4-Hydroxyphenyl)(2-nitrophenyl)methanone, also known as 2-nitrodiphenylmethanone or 2-nitrodiphenylketone, is an organic compound with the chemical formula C13H9NO4. It is a yellow crystalline solid that is soluble in organic solvents such as ethanol and acetone. (4-hydroxyphenyl)(2-nitrophenyl)methanone is formed by the condensation of 4-hydroxybenzaldehyde and 2-nitrobenzaldehyde, and it is an important intermediate in the synthesis of various pharmaceuticals, dyes, and other organic compounds. Due to its reactivity, it is often used in the preparation of various derivatives, such as 2-aminodiphenylmethanone, which is a key intermediate in the synthesis of the antipsychotic drug haloperidol. The compound is also known for its potential applications in the field of materials science, particularly in the development of polymers with specific properties.

61101-88-0

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61101-88-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 61101-88-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,1,0 and 1 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 61101-88:
(7*6)+(6*1)+(5*1)+(4*0)+(3*1)+(2*8)+(1*8)=80
80 % 10 = 0
So 61101-88-0 is a valid CAS Registry Number.

61101-88-0Relevant academic research and scientific papers

Synthesis and biological evaluation of XB-1 analogues as novel histamine H3 receptor antagonists and neuroprotective agents

Bao, Xiaofeng,Jin, Yanyan,Liu, Xiaolu,Liao, Hong,Zhang, Luyong,Pang, Tao

, p. 6761 - 6775 (2014/02/14)

A novel class of H3 receptor antagonists, XB-1 analogues based on benzophenone or oxydibenzene scaffolds were synthesized, and their biological activities were evaluated to determine their in vitro neuroprotective effects against Aβ25-35-induced damage in primary cortical neurons and against glutamate-induced neuronal injury in primary cerebellar granule neurons. The results indicated that all of the tested analogues displayed neuroprotective activity at 0.1 μM or 1 μM. These findings may provide new insights into the development of novel promising H3 receptor antagonists with potential neuroprotective activity.

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