612095-65-5Relevant articles and documents
Synthetic method for preparing amide compounds through co-catalysis of niobium pentachloride and ionic liquid
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Paragraph 0047-0049, (2020/07/13)
The invention relates to a synthetic method for preparing amide compounds through co-catalysis of niobium pentachloride and ionic liquid. The preparation method is characterized by comprising the following steps: weighing organic carboxylic acid, organic amine, niobium pentachloride, ionic liquid and a molecular sieve, adding the materials into a reactor, adding an organic solvent, and reacting for 6-24 hours at the reaction temperature of 70-110 DEG C to obtain a corresponding amide product. The molar ratio of the organic carboxylic acid to the organic amine to the niobium pentachloride to the ionic liquid is 1:(1-3):(0.01-1):(0.05-1); wherein the mass ratio of the organic carboxylic acid to the molecular sieve is 1: (0.2-1). According to the method, the substrate range is expanded, the reaction yield is high (95% or above), the catalyst dosage is small, the atom economy is high, the catalyst is cheap and easy to obtain, the production cost can be greatly reduced, and the method is suitable for industrial production.
NHC-catalyzed C-O or C-N bond formation: Efficient approaches to α,β-unsaturated esters and amides
Zhang, Bo,Feng, Peng,Cui, Yuxin,Jiao, Ning
, p. 7280 - 7282 (2012/07/28)
Simple and efficient NHC-catalyzed transformations of bromoenal or α,β-dibromoenal into α,β-unsaturated esters or amides with high stereoselectivity through C-O or C-N bond formation have been demonstrated. The NHC-catalyzed processes occur under mild con
Some chemical properties of 2,3-dihydro-4H-[1,3]thiazino[3,2-a] benzimidazol-4-one and 2-aryl-2,3-dihydro-4H-[1,3]thiazino[3,2-a]benzimidazol-4- ones
Britsun,Esipenko,Lozinskii
, p. 396 - 402 (2008/02/04)
We have studied the reaction of 2,3-dihydro-4H-[1,3]thiazino[3,2-a] benzimidazol-4-one and 2-aryl-2,3-dihydro-4H-[1,3]thiazino[3,2-a]benzimidazol-4- ones with amines, alkylating reagents, and hydrogen peroxide. We have shown that the presence of an aryl substituent at the 2 position of [1,3-thiazino[3,2-a] benzimidazol-4-ones has a substantial effect on the direction of the reactions. 2006 Springer Science+Business Media, Inc.