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Methyl 2-hydroxy-5-(phenylMethoxy)benzoate, also known as avenzophenone-4, is a chemical compound that belongs to the benzoate esters family. It is commonly used as a UV filter in skincare and cosmetic products due to its ability to absorb and dissipate UVB and UVA rays, providing protection against sun damage and photoaging.

61227-22-3

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61227-22-3 Usage

Uses

Used in Skincare and Cosmetic Industry:
Methyl 2-hydroxy-5-(phenylMethoxy)benzoate is used as a UV filter for its ability to absorb and dissipate UVB and UVA rays, offering protection against sun damage and photoaging. It is often added to sunscreens, moisturizers, and other topical products to enhance their sun protection abilities.
Used in Sunscreen Products:
Methyl 2-hydroxy-5-(phenylMethoxy)benzoate is used as an active ingredient in sunscreens for its effectiveness in filtering harmful UV rays, thus helping to prevent skin damage and premature aging caused by sun exposure.
Used in Moisturizers and Topical Products:
Methyl 2-hydroxy-5-(phenylMethoxy)benzoate is used as a protective agent in moisturizers and other topical products to provide additional sun protection and help maintain the skin's health and appearance.

Check Digit Verification of cas no

The CAS Registry Mumber 61227-22-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,2,2 and 7 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 61227-22:
(7*6)+(6*1)+(5*2)+(4*2)+(3*7)+(2*2)+(1*2)=93
93 % 10 = 3
So 61227-22-3 is a valid CAS Registry Number.

61227-22-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 2-hydroxy-5-phenylmethoxybenzoate

1.2 Other means of identification

Product number -
Other names methyl 2-hydroxy-5-(phenylmethoxy)benzoate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:61227-22-3 SDS

61227-22-3Relevant academic research and scientific papers

POLYCYCLIC AMIDES AS UBE2K MODULATORS FOR TREATING CANCER

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Paragraph 00189-00191, (2021/07/10)

Provided are compounds of Formula (I) and pharmaceutically acceptable salts and compositions thereof, which are useful for treating conditions associated with modulation of UBE2K.

APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS AND USES THEREOF

-

, (2019/04/09)

Described herein are ASK1 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of blood disease, autoimmune disorders, pulmonary disorders, hypertension, inflammatory diseases, fibrotic diseases, diabetes, diabetic nephropathy, renal diseases, respiratory diseases, cardiovascular diseases, acute lung injuries, acute or chronic liver diseases, and neurodegenerative diseases.

Macrocyclic pentamers functionalised around their periphery as potential building blocks

Nam, Seong,Ware, David C.,Brothers, Penelope J.

, p. 8389 - 8393 (2019/03/21)

The elaboration of a five-fold symmetric macrocyclic aromatic pentamer bearing peripheral benzyloxy and hydroxyl groups is described. These could be used to explore further functionalisation for use as pentagonal building blocks. The internal fluorine-substituted macrocycle has been prepared via a one-pot procedure which is an improvement on the stepwise chain growth approach reported in the literature.

BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS

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Page/Page column 47; 48, (2014/10/15)

The present invention relates to compounds of the formula (I), wherein X, R, R1, R2, D, E1, E2, E3, E4, G1, G2, G3 and G4 have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. They are inhibitors of the protease ca

Biaryl-propionic acid derivatives and their use as pharmaceuticals

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Paragraph 0128; 0129, (2014/10/16)

The present invention relates to compounds of the formula I, wherein X, R, R1, R2, D, E1, E2, E3, E4, G1, G2, G3 and G4 have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. They are inhibitors of the protease cath

BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS

-

Page/Page column 47-48, (2014/10/15)

The present invention relates to compounds of the formula (I), wherein X, R, R1, R2, D, E1, E2, E3, E4, G1, G2, G3 and G4 have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. They are inhibitors of the protease ca

Biaryl-Propionic Acid Derivatives and their Use as Pharmaceuticals

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Paragraph 0137; 0138; 0139, (2014/10/16)

The present invention relates to compounds of the formula I, wherein X, R, R1, R2, D, E1, E2, E3, E4, G1, G2, G3 and G4 have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. They are inhibitors of the protease cath

THIOCHROMENE DERIVATIVES AS HIP HYDROXYLASE INHIBITORS

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Page/Page column 90, (2010/06/15)

The present invention relates to novel compounds, methods, and compositions capable of decreasing HEF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF).

IMIDAZOPYRIDINE COMPOUNDS

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Page/Page column 23, (2010/04/23)

Compounds, pharmaceutical compositions, kits and methods are provided for use with glucokinase that comprise a compound selected from the group consisting of formula (I) wherein the variables are as defined herein.

Conception of myeloperoxidase inhibitors derived from flufenamic acid by computational docking and structure modification

Van Antwerpen, Pierre,Prevost, Martine,Zouaoui-Boudjeltia, Karim,Babar, Sajida,Legssyer,Moreau, Patrick,Moguilevsky, Nicole,Vanhaeverbeek, Michel,Ducobu, Jean,Neve, Jean,Dufrasne, Francois

, p. 1702 - 1720 (2008/09/20)

The development of myeloperoxidase (MPO) inhibitors has been conducted using flufenamic acid as a lead compound. Computational docking of the drug and its analogs in the MPO active site was first attempted. Several molecules were then synthesized and assessed using three procedures for the measurement of their inhibiting activity: (i) the taurine assay, (ii) the accumulation of compound II, and (iii) the LDL oxidation by ELISA. Most of the synthesized molecules had an activity in the same range as flufenamic acid but none of them were able to inhibit the MPO-dependent LDL oxidation. The experiments however gave some useful indications for a rational conception of MPO inhibitors.

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