6141-21-5Relevant academic research and scientific papers
Platinum metal complexes with divalent groups bridging two ligands
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Page/Page column 50, (2017/07/04)
The present invention relates to metal complexes and to electronic devices, in particular organic electroluminescent devices, comprising these metal complexes.
TBHP/CoCl2-mediated intramolecular oxidative cyclization of N-(2-formylphenyl)amides: An approach to the construction of 4H-3,1-benzoxazin-4-ones
Yu, Junchao,Zhang-Negrerie, Daisy,Du, Yunfei
, p. 562 - 568 (2016/02/18)
The intramolecular oxidative cyclization of N-(2-formylphenyl)amides has been realized through an oxidative C(sp2)-O(sp2) bond-forming reaction between an aldehyde carbon and amide oxygen. This new strategy, which uses tert-butyl hydroperoxide (TBHP) as an oxidant and CoCl2 as the catalyst, allows for the efficient Co-catalyzed synthesis of useful benzoxazin-4-one derivatives and features readily available starting materials and mild reaction conditions. The intramolecular cyclization of N-(2-formylphenyl)amides has been realized through an oxidative C(sp2)-O(sp2) bond-forming reaction between an aldehyde carbon and amide oxygen. This new strategy, which uses tert-butyl hydroperoxide (TBHP) as the oxidant and CoCl2 as the catalyst, allows for the efficient Co-catalyzed synthesis of useful benzoxazin-4-one derivatives.
Metal complex
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Paragraph 0153; 0154, (2016/10/08)
The present invention relates to metal complexes and to electronic devices, in particular organic electroluminescent devices, comprising these metal complexes.
KOtBu-mediated stereoselective addition of quinazolines to alkynes under mild conditions
Zhao, Dan,Shen, Qi,Zhou, Yu-Ren,Li, Jian-Xin
supporting information, p. 5908 - 5912 (2013/09/12)
A facile alkenylation of quinazolines with unactivated terminal alkynes has been achieved in the presence of KOtBu without the aid of any transition metal catalysts. The reaction is carried out under very mild conditions and shows a high stereoselectivity
Friedlaender Synthesis of Substituted Quinolines from N-Pivaloylanilines
Ubeda, J. Ignacio,Villacampa, Mercedes,Avendano, Carmen
, p. 1176 - 1180 (2007/10/03)
Synthesis of a great variety of quinoline derivatives has been developed by lithiation of N-pivaloylanilines with sec-BuLi, formylation with DMF, and subsequent condensation with active methylene groups of aldehydes or ketones (KHMDS).The pivaloyloxy group is eliminated during one-pot procedure in most cases.The scope of the reaction has been studied, showing that the method is limited by the nature of intermediate compounds. - Keywords: Friedlaender synthesis; pivaloylanilines; quinolines; o-metalation; one-pot synthesis
Uses of aza-cope rearrangement-mannich cyclization reactions to achieve a general entry to melodinus and aspidosperma alkaloids. stereocontrolled total syntheses of (±)-deoxoapodine, (±)-meloscine, and (±)-epimeloscine and a formal synthesis of (±)-1-acetylaspidoalbidine
Overmann, Larry E.,Robertson, Graeme M.,Robichaud, Albert J.
, p. 2598 - 2610 (2007/10/02)
The first total syntheses of the structurally unusual pentacyclic Melodinus alkaloids (±)-meloscine (1) and (±)-epimeloscine (2) and the hexacyclic Aspidosperma alkaloids (±)-deoxoapodine (4) are reported. The syntheses proceed via a highly functionalized common tetracyclic intermediate 7, which is accessed (with complete stereocontrol) by the title rearrangement of pyrindinol 10. These syntheses provide excellent examples of the power of tandem of aza-Cope rearrangement-Mannich cyclization reactions as the key element of stereocontrolled alkaloid synthesis design.
Synthesis Applications of Cationic Aza-Cope Rearrangements. Stereocontrolled Synthesis of Hexahydro-1H-pyrrolocarbazoles
Overman, Larry E.,Angle, Steven R.
, p. 4021 - 4028 (2007/10/02)
The synthesis of a series of 5-substituted octahydro-1H-pyrrolocarbazoles 4, potential intermediates for the synthesis of the Strychnos alkaloid akuammicine 2, is described.The known β-keto ester 9 was converted to the (E)-epoxy alcohol 7 in 39perc
