61425-27-2 Usage
Description
N-Benzyloxycarbonyl-D-alaninol is a chemical compound with the molecular formula C14H17NO4. It is a derivative of D-alanine, an essential amino acid for protein synthesis. N-Benzyloxycarbonyl-D-alaninol features a benzyloxycarbonyl group (Z group) that protects the amine group, enabling selective reactions at other functional groups. N-Benzyloxycarbonyl-D-alaninol is widely utilized in the synthesis of peptide and protein derivatives, as well as in the production of pharmaceuticals and bioactive compounds, serving as a crucial building block in various chemical and pharmaceutical applications.
Uses
Used in Pharmaceutical Industry:
N-Benzyloxycarbonyl-D-alaninol is used as a key intermediate in the synthesis of pharmaceuticals for its ability to protect the amine group during the synthesis process. This protection allows for the selective formation of desired peptide bonds and the creation of complex molecular structures with enhanced stability and bioavailability.
Used in Peptide Synthesis:
In peptide synthesis, N-Benzyloxycarbonyl-D-alaninol is used as a building block to construct peptide sequences. The Z group on the compound facilitates the stepwise assembly of peptides by preventing unwanted side reactions, thus improving the yield and purity of the final peptide product.
Used in Bioactive Compound Production:
N-Benzyloxycarbonyl-D-alaninol is employed as a precursor in the production of bioactive compounds, such as antibiotics, enzymes, and other therapeutic agents. Its role in protecting the amine group during synthesis contributes to the development of more effective and targeted biologically active molecules.
Used in Chemical Research:
In the field of chemical research, N-Benzyloxycarbonyl-D-alaninol is utilized as a reagent and a model compound for studying the properties and reactions of amino acids and their derivatives. Its unique structure and functional groups make it an invaluable tool for understanding the fundamental principles of organic and biochemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 61425-27-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,4,2 and 5 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 61425-27:
(7*6)+(6*1)+(5*4)+(4*2)+(3*5)+(2*2)+(1*7)=102
102 % 10 = 2
So 61425-27-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H15NO3/c1-9(7-13)12-11(14)15-8-10-5-3-2-4-6-10/h2-6,9,13H,7-8H2,1H3,(H,12,14)/t9-/m1/s1
61425-27-2Relevant articles and documents
RHO KINASE INHIBITOR, METHOD FOR PREPARING SAME AND USES THEREOF
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Paragraph 0130, (2021/09/16)
Provided are a Rho kinase inhibitor, a method for preparing same and the uses thereof. The Rho kinase inhibitor designates a compound of Formula I, a stereoisomer thereof or pharmaceutically acceptable salt thereof. The Rho kinase inhibitor promotes endothelial cells and endothelin expression, prostenin expression, and vascular factors NO synthesis and secretion, has a promoting effect on proprostin expression independently of the doses used, shows lower toxicity, while being safer.
SuFExable Isocyanides for Ugi Reaction: Synthesis of Sulfonyl Fluoro Peptides
Xu, Shuheng,Cui, Sunliang
supporting information, p. 5197 - 5202 (2021/07/20)
Herein, the sulfonyl fluoro isocyanides were first developed as a new type of SuFExable synthon, and they are used as building blocks in the Ugi reaction (U-4CR). The Ugi reaction was established and the substrate scope was investigated, and various sulfonyl fluoro α-amino amides and peptides could be reached in a one-step synthesis. Therefore, this protocol opens a new vision for SuFExable building blocks and click chemistry, and it also provides a distinct approach to sulfonyl fluoro peptides.
Chiral pyrazole derivative and synthesis method thereof
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Paragraph 0027-0029; 0040-0042; 0053-0055, (2020/06/20)
The invention belongs to the technical field of organic synthesis, and discloses a chiral pyrazole derivative and a synthesis method thereof. The chiral pyrazole derivative is (1-(4'-amino-5'-carbamoyl-1'-pyrazolyl)-(S)-2-propyl-benzyloxy amide. The synth
