61524-51-4

Usage

Uses

Used in Pharmaceutical Industry:
4,6-dibromobenzene-1,3-diol is used as a reactant in the synthesis of pharmaceuticals due to its antimicrobial and antifungal properties. It contributes to the development of new drugs that can combat a range of microbial infections.
Used in Dye Industry:
In the dye industry, 4,6-dibromobenzene-1,3-diol is utilized as a reactant for the production of dyes. Its chemical structure allows for the creation of dyes with specific color properties, enhancing the range of colorants available for various applications.
Used in Organic Synthesis:
4,6-dibromobenzene-1,3-diol is used as a reactant in organic synthesis for the preparation of various organic compounds. Its unique structure facilitates a wide range of chemical reactions, making it a useful building block in the synthesis of complex organic molecules.
Used in Agrochemical Industry:
As a precursor in the agrochemical industry, 4,6-dibromobenzene-1,3-diol is used in the synthesis of biologically active compounds. Its properties enable the development of new agrochemicals that can be employed in pest control and crop protection.
Used in Chemical Reactions:
4,6-dibromobenzene-1,3-diol serves as a precursor in various chemical reactions within the pharmaceutical and agrochemical industries. Its role in these reactions is crucial for the production of a multitude of compounds that have significant applications in these sectors.

InChI:InChI=1/C6H4Br2O2/c7-3-1-4(8)6(10)2-5(3)9/h1-2,9-10H

Upstream product

• 2437-49-2 2,4,6-tribromoresorcinol 
• 108-46-3 recorcinol 
• 75-15-0 carbon disulfide 
• 7726-95-6 bromine 
• 64-19-7 acetic acid 
• 36942-09-3 N,N-dichlorourea 
• 7664-93-9 sulfuric acid 
• 136-36-7 benzoate d'hydroxy-3 phenyle 
• 6626-15-9 4-Bromoresorcinol 
• 856079-32-8 5-benzoyloxy-2,4-dibromo-phenol 

Downstream Products

• 24988-36-1 4,6-dibromo-1,3-dimethoxybenzene 
• 108-46-3 recorcinol 
• 25676-73-7 2,4,6-tribromo-1,3-dimethoxybenzene 
• 2437-49-2 2,4,6-tribromoresorcinol 
• 89-86-1 4-hydroxysalicylic acid 
• 6626-15-9 4-Bromoresorcinol 

Relevant academic research and scientific papers

Structural and energetic effect of the intramolecular hydrogen bonding in 4,6-dihaloresorcinols: ab initio calculation, vibrational spectroscopy, and molecular docking studies

The intramolecular hydrogen bonding in the series of 4,6-dihaloresorcinols (with halogen atoms being F, Cl, Br, or I) is believed to play a noticeable role in determining the structural and electronic aspects. All theoretical levels employed in this work

Method for photocatalytic synthesis of polybrominated phenol compound in water phase

The invention discloses a method for photocatalytic synthesis of a polybrominated phenol compound in a water phase, comprising the following steps: adding a catalytic amount of a radical initiator, aphenol derivative and low-toxic and cheap bromide salt and water into a reaction vessel, reacting at room temperature at 5 W power in a photocatalytic reactor for a certain period, extracting with ethyl acetate and then re-crystallizing to obtain a polybrominated phenol compound. The above radical initiator is eosin, azobisisobutanol, sodium persulfate, ammonium persulfate or potassium persulfate.The free radical initiator and the bromine salt are cheap and easily available, and the method is an ideal synthesis method of the polybrominated phenol compound. According to the method, low-toxicity bromine salt instead of liquid bromine is used to carry out a bromination reaction, unstable and explosive hydrogen peroxide is replaced with the cheap and easily-available free radical initiator, and an emerging photocatalytic method is used. The polybrominated phenol compound can be obtained in a high yield by only using a 5W power lamp for the reaction, the reaction selectivity is high, by-products are less, and the post-treatment is simple.

Synthesis of phenylethynylbenzenes

A method of: reacting a dihydroxybenzene with bromine to form a bromodihydroxybenzene; reacting the bromodihydroxybenzene with trifluoromethanesulfonyl chloride or trifluoromethanesulfonic anhydride to form a bromotrifluoromethanesulfonatobenzene; and reacting the bromotrifluoromethanesulfonatobenzene with phenylacetylene to form a phenylethynylbenzene.

AROMATIC POLYACETALS AND ARTICLES COMPRISING THEM

A polymer includes repeat units having the structure wherein R1, R2, Ar1, Ar2, and Ar3 are defined herein. The polymer can be prepared by Suzuki polycondensation. The acetal and/or ketal functionality

Bromination of aromatic compounds using ammonium bromide and oxone

A simple, efficient and mild method for the selective bromination of activated aromatic compounds using ammonium bromide as the source of bromine and Oxone as the oxidant in methanol or water as solvent is reported. The reaction proceeds at ambient temperature in yields ranging from moderate to excellent without a catalyst. Georg Thieme Verlag Stuttgart.

Vanadium-catalyzed oxidative bromination promoted by Br?nsted acid or Lewis acid

The oxidative bromination of arenes was induced by a vanadium catalyst in the presence of a bromide salt and a Br?nsted acid or a Lewis acid under molecular oxygen, which provides an eco-friendly bromination method as compared with a conventional bromination one with bromine. This catalytic reaction could be applied to the bromination of alkenes and alkynes to give the corresponding vic-bromides. Use of aluminum halide as a Lewis acid in place of a Br?nsted acid was demonstrated to provide a more practical protocol for the oxidative bromination. From ketones, α-bromination products were obtained. AlBr3 was found to serve as both a bromide source and a Lewis acid to induce the bromination smoothly. 51V NMR experiment showed that this catalytic bromination is likely to depend on the redox cycle of a vanadium catalyst under molecular oxygen.

Oxidative bromination reaction using vanadium catalyst and aluminum halide under molecular oxygen

The vanadium-catalyzed oxidative bromination reaction of arenes, alkenes, and alkynes was performed in the presence of AlBr3 to provide an alternative method for conventional bromination using hazardous bromine. The catalytic cycle is formed under molecular oxygen, which is more advantageous to vanadium bromoperoxidase (VBrPO) requiring hydrogen peroxide as a terminal oxidant.

Total synthesis of psoralidin, an anticancer natural product

A base-catalyzed condensation of phenyl acetate with acid chloride, followed by intramolecular cyclization and microwave-assisted cross-metathesis reaction, leads to the first total synthesis of psoralidin, a natural product with a broad range of biological activities, in a highly convergent and regioselective manner.

Investigations into the bromination of substituted phenols using diethyl bromomalonate and diethyl dibromomalonate

Substituted 4-bromophenols can be synthesised efficiently by heating the corresponding phenol in either neat diethyl bromomalonate or diethyl dibromomalonate. We discuss the regioselectivity of such reactions and comment on the scope and limitation of this procedure.

Selective halogenation of aromatics by dimethyldioxirane and halogen ions

The oxidation of halogen anions by dimethyldioxirane (DMD) produced reactive species which led, in acidic media, to the halogenation of activated aromatic rings. The reaction can be efficiently controlled to obtain selective and mixed halogenated species.