616209-43-9

Basic information

• Product Name: 1-(4-(methylthio)phenyl)-5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazole
• Synonyms: 1-(4-(methylthio)phenyl)-5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazole
• CAS NO: 616209-43-9
• Molecular Weight: 348.392
• Mol File: 616209-43-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(4-(methylthio)phenyl)-5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-(methylthio)phenyl)-5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazole(616209-43-9)
• EPA Substance Registry System: 1-(4-(methylthio)phenyl)-5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazole(616209-43-9)

Safety Data

• Hazardous Substances Data: 616209-43-9(Hazardous Substances Data)

Upstream product

• 624-92-0 Dimethyldisulphide 
• 104-96-1 4-methylsulfanylaniline 
• 122-00-9 para-methylacetophenone 
• 720-94-5 4,4,4-trifluoro-1-(4-methylphenyl)butane-1,3-dione 
• 58626-97-4 [p-(methylthio)phenyl]hydrazine hydrochloride 

Downstream Products

• 190711-47-8 1-(4-Methanesulfinyl-phenyl)-5-p-tolyl-3-trifluoromethyl-1H-pyrazole 
• 675605-72-8 1-(4-(methylsulfonyl)phenyl)-5-(4-methylphenyl)-3-(trifluoromethyl)-1Hpyrazole 

Relevant articles and documents

Nickel-Catalyzed Reversible Functional Group Metathesis between Aryl Nitriles and Aryl Thioethers

We describe a new functional group metathesis between aryl nitriles and aryl thioethers. The catalytic system nickel/dcype is essential to achieve this fully reversible transformation in good to excellent yields. Furthermore, the cyanide- and thiol-free reaction shows high functional group tolerance and great efficiency for the late-stage derivatization of commercial molecules. Finally, synthetic applications demonstrate its versatility and utility in multistep synthesis.

NEW HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN MEDICINE

The present invention describes novel compounds having antiinflammatory activity, process for their preparation and pharmaceutical composition containing them.