617-79-8

Basic information

• Product Name: 2-Ethylbutylamine
• Synonyms: 1-amino-2-ethylbutane;2-ethyl-1-butanamin;2-ethyl-butylamin;2-ETHYLBUTYLAMINE;2-ETHYL-N-BUTYLAMINE;2-Ethylbutylamine,97%;2-Ethyl-1-butylamine, 97%;2-Ethyl-N-butylamine ,98%
• CAS NO: 617-79-8
• Molecular Formula: C₆H₁₅N
• Molecular Weight: 101.19
• EINECS: 210-530-6
• Mol File: 617-79-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 20°C
• Boiling Point: 125
• Flash Point: 14 °C
• Appearance: /
• Density: 0.776
• Vapor Pressure: 16.6mmHg at 25°C
• Refractive Index: 1.4100
• Storage Temp.: Flammables area
• PKA: 10.75±0.10(Predicted)
• Water Solubility: Soluble in water at 25°C 3.83E+04 mg/L.
• Sensitive: Air Sensitive
• CAS DataBase Reference: 2-Ethylbutylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Ethylbutylamine(617-79-8)
• EPA Substance Registry System: 2-Ethylbutylamine(617-79-8)

Safety Data

• Hazard Codes: C-F,F,C,Xn
• Statements: 34-20/21/22-11-36-22
• Safety Statements: 45-36/37/39-26-16
• RIDADR: 2733
• RTECS: EO4900000
• HazardClass: 3
• PackingGroup: II
• Hazardous Substances Data: 617-79-8(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless to light yellow liquid

Uses

Different sources of media describe the Uses of 617-79-8 differently. You can refer to the following data:
1. Isohexylamine is used in organic syntheses.
2. 2-Ethylbutylamine is used in preparation of Amide-substituted Heterocyclic compounds for the treatment of conditions related to the modulation of IL-12, IL-23 and/or IFN-alpha.

Safety Profile

Poison by ingestion. Moderately toxic by skin contact. A skin and severe eye irritant. A very dangerous fire hazard when exposed to heat or flame; can react vigorously with oxidizing materials. Keep away from heat and open flame. To fight fire, use dry chemical, CO2, foam. When heated to decomposition it emits toxic fumes of NOx. See also AMINES.

InChI:InChI=1/C6H15N/c1-3-6(4-2)5-7/h6H,3-5,7H2,1-2H3

Upstream product

• 88-09-5 2-Ethylbutanoic acid 
• 1114-38-1 2-ethylbutanamide 
• 7664-41-7 ammonia 
• 3814-34-4 2-ethyl-1-bromobutane 
• 617-80-1 2-ethyl-butyronitrile 
• 4411-91-0 2-ethyl-crotonic acid amide 
• 5399-18-8 2-ethylbutyraldehyde oxime 

Downstream Products

• 145889-28-7 methyl 4-<<5-<(2-ethylbutyl)carbamoyl>indol-3-yl>methyl>-3-methoxybenzoate 
• 145889-25-4 methyl 4-<<5-<(2-ethylbutyl)carbamoyl>-1-methylindol-3-yl>methyl>-3-methoxybenzoate 
• 106-98-9 1-butylene 
• 1019620-28-0 N-(2-ethylbutyl)cyclohexanamine 
• 1066867-56-8 C₃₀H₃₉N₃O₇S₂ 
• 1066867-54-6 C₂₉H₄₁N₃O₇S 
• 1066867-53-5 C₃₀H₄₂N₂O₈S 
• 1066867-57-9 C₃₀H₄₂N₂O₈S 
• 1066867-55-7 C₃₀H₄₀N₂O₉S 
• 531506-81-7 2-Chloro-5-(3,5-dioxo-4,5-dihydro-3H-[1,2,4]triazin-2-yl)-N-(2-ethyl-butyl)-benzamide 
• 1283599-86-9 C₃₇H₃₄N₂O₇ 
• 1283599-73-4 C₄₂H₃₆N₂O₆S 
• 1283599-78-9 C₂₈H₂₂N₂O₄ 
• 1283599-77-8 C₂₆H₂₁IN₂O₄ 

Relevant articles and documents

One-pot reductive amination of carboxylic acids: a sustainable method for primary amine synthesis

The reductive amination of carboxylic acids is a very green, efficient and sustainable method for the production of (bio-based) amines. However, with current technology, this reaction requires two to three reaction steps. Here, we report the first (heterogeneous) catalytic system for the one-pot reductive amination of carboxylic acids to amines, with solely H2 and NH3 as the reactants. This reaction can be performed with relatively cheap ruthenium-tungsten bimetallic catalysts in the green and benign solvent cyclopentyl methyl ether (CPME). Selectivities of up to 99% for the primary amine could be achieved at high conversions. Additionally, the catalyst is recyclable and tolerant for common impurities such as water and cations (e.g. sodium carboxylate).