620-47-3

Usage

Uses

Used in Chemical Industry:
3-Benzyl toluene is used as a solvent for various chemical processes, facilitating the dissolution of other substances and enabling reactions to occur more efficiently.
Used in Dye Production:
3-Benzyl toluene is used as a raw material in the production of dyes, contributing to the creation of a diverse range of colorants for different applications.
Used in Perfumery:
3-Benzyl toluene is used as a raw material in the production of perfumes, leveraging its sweet, floral scent to enhance fragrance compositions.
Used in Pharmaceutical Industry:
3-Benzyl toluene is used as a raw material in the production of pharmaceuticals, playing a role in the synthesis of various medicinal compounds.
It is important to handle 3-benzyl toluene with care due to its potential health risks, ensuring safety in all applications where it is utilized.

InChI:InChI=1/C14H14/c1-12-6-5-9-14(10-12)11-13-7-3-2-4-8-13/h2-10H,11H2,1H3

Upstream product

• 643-65-2 3-methyl benzophenone 
• 62441-37-6 4-benzyl-2-methylbenzenamine 
• 854861-62-4 3-dichloromethyl-benzhydryl chloride 
• 871877-28-0 dichloro-phenyl-(3-trichloromethyl-phenyl)-methane 
• 137474-24-9 3-methylbenzhydrol 
• 5467-99-2 4-methylbenzoic acid benzyl ester 
• 106-42-3 para-xylene 
• 100-44-7 benzyl chloride 
• 108-88-3 toluene 
• 71-43-2 benzene 
• 593-53-3 Methyl fluoride 
• 101-81-5 Diphenylmethane 
• 350-50-5 benzyl fluoride 
• 770-09-2 benzyltrimethylsilane 

Downstream Products

• 67277-76-3 2,2',4,4'-Tetranitro-5-methyl-diphenylmethan 
• 36343-06-3 C₁₄H₉N₅O₁₀ 
• 86846-59-5 (3-Methyldiphenylmethyl)lithium 
• 579-18-0 3-benzoylbenzoic acid 
• 643-65-2 3-methyl benzophenone 
• 66826-97-9 1-cyclohexylmethyl-3-methyl-cyclohexane 
• 1169764-41-3 methyl 2-methoxy-5-(phenyl(m-tolyl)methyl)benzoate 
• 1438894-51-9 m-methylphenylphenylmethanol acetate 
• 1326231-73-5 1-(phenyl(m-tolyl)methyl)-1H-benzo[d]imidazole 
• 68392-13-2 2.2'.4.4'-Tetranitro-5-styryl-diphenylmethan 
• 106147-61-9 4-(2-Phenyl-2-m-tolyl-ethyl)-1H-imidazole 

Relevant academic research and scientific papers

Continuous flow preparation of iron oxide nanoparticles supported on porous silicates

A simple, innovative, and efficient continuous flow methodology for the direct preparation of supported nanoparticles on porous materials by using metal precursor solution flowing through heated packed-bed reactors containing the support material has been developed. The effects of the flow rate of the precursor solution, temperature, and nature of the support material and metal loading have been investigated. Results indicated that optimum conditions comprised short residence times (with typical flow rates of 0.5 mL min-1 and below) under mild heating (100 ?°C) to achieve optimum materials in terms of nanoparticle size and structure and catalytic activity. The support was found to have a remarkable effect on both loading and distribution and agglomeration of nanoparticles in the system, with a previously reported Fe/Al synergy also observed in the prepared nanomaterials, which led to optimum results.

New bio-nanocomposites based on iron oxides and polysaccharides applied to oxidation and alkylation reactions

Polysaccharides from natural sources and iron precursors were applied to develop new bio-nanocomposites by mechanochemical milling processes. The proposed methodology was demonstrated to be advantageous in comparison with other protocols for the synthesis of iron oxide based nanostructures. Additionally, mechanochemistry has enormous potential from an environmental point-of-view since it is able to reduce solvent issues in chemical syntheses. The catalytic activity of the obtained nanocatalysts was investigated in both the oxidation of benzyl alcohol to benzaldehyde and in the alkylation of toluene with benzyl chloride. The microwave-assisted oxidation of benzyl alcohol reached 45% conversion after 10 min. The conversion of the alkylation of toluene in both microwave-assisted and conventional heating methods was higher than 99% after 3 min and 30 min, respectively. The transformation of benzyl alcohol and toluene into valuable product in both the oxidation and alkylation reaction reveals a potential method for the valorization of lignocellulosic biomass.

Insights into the active species of Nanoparticle-functionalized hierarchical zeolites in alkylation reactions

Supported iron oxide nanoparticles have been incorporated onto hierarchical zeolites by microwave-assisted impregnation and mechanochemical grinding. Nanoparticle-functionalised porous zeolites were characterised by a number of analytical techniques such as XRD, N2 physisorption, TEM, and surface acidity measurements. The catalytic activities of the synthesised nanomaterials were investigated in an alkylation reaction. The results pointed to different species with varying acidity and accessibility in the materials, which provided essentially different catalytic activities in the alkylation of toluene with benzyl chloride under microwave irradiation, selected as the test reaction. Iron out the creases: Supported iron oxide nanoparticles are incorporated on hierarchical zeolites by microwave-assisted impregnation and mechanochemical grinding. The catalytic activities of the synthesized nanomaterials are investigated in the alkylation of toluene with benzyl chloride under microwave irradiation.

No contest: A co-reactant deprived of reactivity

Whereas benzyl chloride is normally more reactive than benzyl alcohol toward aromatic hydrocarbons, at 20°C alkylation of toluene is totally inhibited in the presence of an equimolar mixture of the two benzylating agents and of a clay-based catalyst. At 80°C, all the alcohol molecules are first consumed. Then, and only then, at time T = 45 mn, the chloride molecules start their reaction.

Conversion of Aryl Aldehydes to Benzyl Iodides and Diarylmethanes by H3PO3/I2

For the first time, H3PO3 was used as both the reducing reagent and the promotor in the reductive benzylation reactions with aryl aldehydes. By using a H3PO3/I2 combination, various aromatic aldehydes underwent iodination reactions and Friedel-Crafts type reactions with arenes via benzyl iodide intermediates, readily producing benzyl iodides and diarylmethanes in good yields. Intramolecular cyclization reactions also took place, giving the corresponding cyclic compounds. This new strategy features easy-handling, low-cost, and metal-free conditions.

Method for reducing carbonyl reduction to methylene under illumination

The invention belongs to the technical field of organic chemical synthesis. The method comprises the following steps: (1) mixing the carbonyl compound and the amine compound in a solvent, reacting 3 - 6 under the illumination of 380 - 456 nm, the reaction system is low in toxicity, high in atom utilization rate 12 - 24h. and production efficiency, safe and controllable in reaction process and capable of simplifying the operation in the preparation and production process. At the same time, the residue toxicity of the reaction is minimized, the pollution caused by the production process to the environment is reduced, and the steps and operations of removing residues after the reaction are simplified. In addition, the reactant feedstock is readily available. The reactant does not need additional modification before the reaction, can be directly used for preparing production, simplifies the operation steps, and shortens the reaction route. The production cost is obviously reduced.

Photo-Ni-Dual-Catalytic C(sp2)-C(sp3) Cross-Coupling Reactions with Mesoporous Graphitic Carbon Nitride as a Heterogeneous Organic Semiconductor Photocatalyst

The synergistic combination of a heterogeneous organic semiconductor mesoporous graphitic carbon nitride (mpg-CN) and a homogeneous nickel catalyst with visible-light irradiation at room temperature affords the C(sp2)-C(sp3) cross-co

Phosphonic acid mediated practical dehalogenation and benzylation with benzyl halides

For the first time, by using H3PO3/I2 system, various benzyl chlorides, bromides and iodides were dehalogenated successfully. In the presence of H3PO3, benzyl halides underwent electrophilic substitution reactions with electron-rich arenes, leading to a broad range of diarylmethanes in good yields. These transformations feature green, cheap reducing reagents and metal-free conditions. A possible mechanism was proposed.

Super electron donor-mediated reductive desulfurization reactions

The desulfurization of thioacetals and thioethers by a pyridine-derived electron donor is described. This methodology provides efficient access to the reduced products in high yields and does not require the use of transition-metals, elemental alkali-metals, or hydrogen atom donors.

Ni(NIXANTPHOS)-Catalyzed Mono-Arylation of Toluenes with Aryl Chlorides and Bromides

A nickel-catalyzed cross-coupling of toluene derivatives with both aryl bromides and chlorides using a NIXANTPHOS-ligated nickel(II) complex has been developed. The key factor to success is proposed to be the catalyst activation of toluene by a cation-π complex, enabling methyl arenes (pKa ≈ 43) to be deprotonated with the relatively mild base NaN(SiMe3)2. This method facilitates access to a variety of sterically and electronically diverse hetero- and nonheteroaryl-containing diarylmethanes.