Tetrahedron Letters p. 2903 - 2904 (1991)
Update date:2022-08-29
Topics:
Cornelis, Andre
Dony, Charles
Laszlo, Pierre
Nsunda, Kinkela M.
Whereas benzyl chloride is normally more reactive than benzyl alcohol toward aromatic hydrocarbons, at 20°C alkylation of toluene is totally inhibited in the presence of an equimolar mixture of the two benzylating agents and of a clay-based catalyst. At 80°C, all the alcohol molecules are first consumed. Then, and only then, at time T = 45 mn, the chloride molecules start their reaction.
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