620-89-3Relevant articles and documents
Diarylamine Synthesis via Desulfinylative Smiles Rearrangement
Sephton, Thomas,Large, Jonathan M.,Butterworth, Sam,Greaney, Michael F.
, p. 1132 - 1135 (2022/02/09)
Diarylamines are obtained directly from sulfinamides through a novel rearrangement sequence. The transformation is transition metal-free and proceeds under mild conditions, providing facile access to highly sterically hindered diarylamines that are otherw
NaBHT Generated in Situ from BHT and NaO tBu: Crystallographic Characterization and Applications in Buchwald-Hartwig Amination
Semeniuchenko, Volodymyr,Ovens, Jeffrey S.,Braje, Wilfried M.,Organ, Michael G.
, p. 3276 - 3290 (2021/10/12)
NaBHT is a valuable medium-strength base useful for many applications, particularly for Buchwald-Hartwig coupling. The structures of solvent-free NaBHT and its solvates with Et2O, THF, tBuOH, and a THF/tBuOH mixture were established using single-crystal X-ray diffraction. While [NaBHT·Et2O]2 adopts a dimeric structure and crystallizes in a monoclinic cell, [NaBHT·THF]3, [NaBHT·tBuOH]3, and [NaBHT·(THF-tBuOH)]3 prefer a trimeric structure and crystallize in cubic cells. Solvent-free [NaBHT]n is different from solvated NaBHT and from other known sodium phenolates. It is an inorganic polymer that crystallizes in an orthorhombic cell, with a NaO core spreading in the [1 0 0] direction. Agostic interactions of the tBu group hydrogens with Na, which were confirmed for all structures, may help explain the reductive properties of NaBHT. Further, interactions of BHT with tBuONa in solution and in the solid state were examined, reveraling that NaBHT does not need to be prepared from pyrophoric NaH or metallic Na every time. Instead, it can be generated efficiently in or ex situ using NaOtBu in solution or with only a stoichiometric amount of solvent to assist in bringing the reactants together. Application of this methodology was demonstrated with the efficient, solvent-free, and Pd-catalyzed C-N coupling with Pd(NHC) catalysts.
Antioxidant and method for preparing antioxidant
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Paragraph 0021; 0046; 0051; 0054; 0059; 0062; 0067, (2021/08/06)
The invention discloses an antioxidant and a method for preparing the antioxidant. An intermediate 2 reacts with an intermediate 5 to obtain an intermediate 14, the intermediate 14 isoxidized with potassium permanganate, an esterification reaction is then carried out with an intermediate 13 to obtain an intermediate 15, the intermediate 15 is reduced with tin powder to obtain an intermediate 16, the intermediate 16 and the intermediate 8 are subjected to dehydration condensation, the antioxidant is prepared, the antioxidant contains a large number of sulfur atoms, the sulfur atoms can be oxidized to form sulfoxide and sulfone compounds, the antioxidant has good oxidation resistance, free radicals generated by macromolecules can be captured, then the free radical branching reaction is inhibited, and the antioxidant activity is improved. The oxidation resistance of the high-molecular material is improved, and the self relative molecular mass is large and is not easy to separate out from the high-molecular material.
