62045-83-4Relevant academic research and scientific papers
Iminoxyl Radical-Promoted Oxycyanation and Aminocyanation of Unactivated Alkenes: Synthesis of Cyano-Featured Isoxazolines and Cyclic Nitrones
Chen, Fei,Zhu, Fei-Fei,Zhang, Man,Liu, Rui-Hua,Yu, Wei,Han, Bing
supporting information, p. 3255 - 3258 (2017/06/23)
A novel and facile approach to vicinal oxycyanation and aminocyanation of internal unactivated alkenes is developed. This method utilizes the dichotomous reactivity of iminoxyl radical derived from the initiation of β,γ- and γ,δ-unsaturated ketoximes to provide the general difunctionalization of internal alkenes using tert-butyl hydroperoxide (TBHP) as the environmentally friendly oxidant, CuCN as the commercially available cyanating reagent, and pentamethyldiethylenetriamine (PMDETA) as the ligand. By using this protocol, a series of useful cyano-featured isoxazolines and cyclic nitrones were efficiently prepared.
α-Regioselective construction of gem-bisprenyl structures via zinc-mediated prenylation of esters in THF
Zhao, Li-Ming,Wan, Li-Jing,Zhang, Shu-Qing,Sun, Rui,Ma, Feng-Yan
, p. 7970 - 7974 (2013/08/23)
The in situ generated prenylzinc reagent from the reaction of zinc with prenyl bromide has been shown to undergo a new type of α-regioselective addition reaction with a wide range of esters that affords gem-bisprenyl structures. The reaction proceeds under mild conditions to provide α,α′-adducts with complete α-regioselectivity. A mechanism with the consideration of the steric factors is proposed to account for the regioselective results.
Reactions with Allylidenephosphoranes, III. Novel Resonance-stabilized Phosphorus Ylides
Capuano, Lilly,Triesch, Thea,Willmes, Arnold
, p. 3767 - 3773 (2007/10/02)
Via the simultaneous reaction of the α- and the γ-position, the allylidenephosphoranes 4 are converted by dicarboxylic acid dichlorides into five- and six-membered isocyclic phosphoranylidenediones 1, 2; by phenyl isothiocyanate into the dithioxo- or imin
