10359-09-8

Basic information

• Product Name: 2-(4-chlorophenyl)-1,3-dithiane
• CAS NO: 10359-09-8
• Molecular Formula: C₁₀H₁₁ClS₂
• Molecular Weight: 230.7773
• Mol File: 10359-09-8.mol
• Article Data: 77

Chemical Properties

• Boiling Point: 355.5°C at 760 mmHg
• Flash Point: 158.7°C
• Density: 1.271g/cm³
• Vapor Pressure: 6.4E-05mmHg at 25°C
• Refractive Index: 1.624
• CAS DataBase Reference: 2-(4-chlorophenyl)-1,3-dithiane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chlorophenyl)-1,3-dithiane(10359-09-8)
• EPA Substance Registry System: 2-(4-chlorophenyl)-1,3-dithiane(10359-09-8)

Safety Data

• Hazardous Substances Data: 10359-09-8(Hazardous Substances Data)

Usage

Dithiane derivative

a compound derived from a dithiane ring, which is a six-membered ring containing two sulfur atoms.

Six-membered ring

the dithiane ring in 2-(4-chlorophenyl)-1,3-dithiane, which consists of six atoms.

Chlorine-substituted phenyl group

a phenyl group (a six-membered ring with alternating single and double bonds) that has a chlorine atom attached to it, which is a common feature in many pharmaceuticals and agrochemicals.

Building block in organic synthesis

2-(4-chlorophenyl)-1,3-dithiane is a commonly used compound in organic synthesis, often utilized as a starting material for the preparation of more complex organic molecules.

Versatile reactivity and stability

the compound's ability to react with a wide range of other chemicals and its resistance to decomposition make it a valuable tool in the development of new chemical compounds in medicinal chemistry and drug discovery.

Upstream product

• 109-80-8 1.3-propanedithiol 
• 6413-52-1 2-(4-chloro-phenyl)-[1,3]dioxane 
• 67-56-1 methanol 
• 104-88-1 4-chlorobenzaldehyde 
• 7099-88-9 4-chlorophenylglyoxylic acid 
• 57529-04-1 2-chloro-1,3-dithiane 
• 772-01-0 2-phenyl-1,3-dioxane 
• 6784-58-3 1-(1,3-dithian-2-ylidene)propan-2-one 
• 2403-54-5 2-(4-chlorophenyl)-1,3-dioxolane 
• 13086-93-6 (acetyloxy)(4-chlorophenyl)methyl acetate 
• 461024-59-9 2-(1,3-dithian-2-ylidene)malonic acid 
• 682360-46-9 2-(1,3-dithian-2-ylidene)-3-oxobutanoic acid 
• 55727-23-6 3‐(1,3-dithiane-2-yl)pentane-2,4-dione 
• 3848-36-0 4-chlorobenzaldoxime 

Downstream Products

• 74955-09-2 [2-(4-Chloro-phenyl)-[1,3]dithian-2-yl]-phenyl-methanone oxime 
• 6573-59-7 1,2,6,7-tetrathiacyclodecane 
• 104-88-1 4-chlorobenzaldehyde 
• 111997-81-0 2-(4-Chlorphenyl)-1,3-dithian-2-ylium-tribromid 
• 461051-86-5 2-(4-chlorophenyl)-2-triethylsilyl-1,3-dithiane 
• 22911-21-3 1-chloro-4-(trimethoxymethyl)benzene 
• 1456628-08-2 2-(2-chloroethyl)-2-(4-chlorophenyl)-1,3-dithiane 
• 1456628-17-3 (R)-4-(4-chlorophenyl)-4-hydroxybutanenitrile 
• 1456628-18-4 (S)-4-(4-chlorophenyl)-4-hydroxybutanenitrile 
• 40394-87-4 4-(4-chloro-phenyl)-4-oxo-butyronitrile 
• 1456628-14-0 3-[2-(4-chlorophenyl)-1,3-dithian-2-yl]propanenitrile 
• 1279712-70-7 C₁₃H₁₇ClOS₂ 
• 1279712-78-5 (Z)-N-(1-(4-chlorophenyl)-1-oxobut-2-en-2-yl)acetamide 
• 51445-67-1 1-(4-chlorophenyl)butane-1,2-dione 

Relevant articles and documents

An uncommon use of irradiated flavins: Br?nsted acid catalysis

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Trichloroisocyanuric acid as a mild and efficient catalyst for thioacetalization and transthio-acetalization reactions

Trichloroisocyanuric acid (1), a cheap industrial chemical, catalyzes mild and efficient thioacetalization and transthioacetalization reactions. In addition, this catalyst is very selective for this purpose.

Investigations towards the chemoselective thioacetaliztion of carbonyl compounds by using ionic liquid [bmim]Br as a recyclable catalytic medium

The ionic liquid based on the 1-n-butyl-3-methylimidazolium cation has been prepared and used as an efficient catalytic medum for the chemoselective thioacetalization of carbonyl compounds. Furthermore, recycling and reuse of this ionic liquid medium has

Mesoporous sBa-15 silica catalyst functionalized with phenylsulfonic acid groups (SbA-15-ph-So3h) as efficient nanocatalyst for chemoselective thioacetalization of carbonyl compounds

In this research a Nano acidic catalyst was prepared and its efficiency on thioacetalization of carbonyl compounds was examined. For this aim we used modified SBA-15 as support, which have been modified by phenolic and sulfonic acid. SBA-15 is a member of

Molybdenum pentachloride (MoCl5) catalyzes efficient dithioacetalization of carbonyl compounds and transdithioacetalization of O, O-acetals. This catalyst also conducts efficient non-hydrolytic deprotection of dithioacetals in the presence of dry DMSO. Part 2

Dithioacetalization of carbonyl compounds was performed efficiently in CH2Cl2 at room temperature in the presence of MoCl5. Highly selective transdithioacetalization of acetals was also catalyzed efficiently by this catalyst. MoCl5 performed non-hydrolytic deprotection of dithioacetals in the presence of dry DMSO.

A Novel Method for Direct Conversion of Carboxylic Acids to 1,3-Dithianes by 1,3,2-Dithiaborinane-Dimethyl Sulfide and Stannous Chloride

Reaction of carboxylic acids with 1,3,2-dithiaborinane-dimethyl sulfide in the presence of stannous chloride in tetrahydrofuran affords the corresponding 1,3-dithianes in high yields.

A mild and efficient method for the protection of carbonyl compounds as oxathiolanes, dithiolanes and dithianes catalyzed by molybdenyl acetylacetonate

Carbonyl compounds have been successfully converted into their corresponding oxathiolane, dithiolane and dithiane derivatives in excellent yields with 2-mercaptoethanol, 1,2-ethanedithiol and 1,3-propanedithiol using a catalytic amount of molybdenyl acety

Dithioacetalization of carbonyl compounds under catalyst-free condition

Protection of carbonyl compounds with 1,3-propanedithiol under a catalyst-free condition in nitromethane as a solvent has been described.

An expedient carbon–sulfur bond formation explored through the cellulose sulfonic acid (CSA) catalyzed dithioacetal protection of carbonyl compounds

A facile carbon–sulfur bond formation was observed through the cellulose sulfonic acid (CSA) catalyzed dithioacetal protection of carbonyl compounds. In a preliminary study, the synthesis and characterization of functionalized bio-polymer, cellulose sulph

Mild and efficient chemoselective protection of aldehydes as dithioacetals employing N-bromosuccinimide

A mild and chemoselective dithioacetalization procedure for the protection of aromatic, aliphatic, and alkenyl aldehydes in presence of catalytic amount of N-bromosuccinimide under neutral conditions is described.

Chemoselective thioacetalization using 3-(1,3-dithian-2-ylidene)pentane-2, 4-dione as an odorless and efficient propane-1,3-dithiol equivalent under solvent-free conditions

As a non-thiolic, odorless propane-1,3-dithiol equivalent, 3-(1,3-dithian-2-ylidene)pentane-2,4-dione has been investigated in acid-promoted thioacetalization under solvent-free conditions. A range of selected aldehydes and aliphatic ketones have been converted into the corresponding dithioacetals in high yields. The relatively slow reaction rate of aromatic ketones allowed chemoselective protection of aromatic aldehydes or aliphatic ketones, in contrast to aromatic ketones. Georg Thieme Verlag Stuttgart.

Visible-Light-Induced in Situ Generation of Fischer-Type Copper Carbene Complexes from Acylsilanes and Its Application to Catalytic [4 + 1] Cycloaddition with Siloxydienes

A novel methodology for in situ generation of Fischer-type metal–carbene complexes was developed. Photoirradiation to a mixture of an acylsilane and a cationic copper complex cleanly gave a Fischer-type copper–siloxycarbene complex, which was detected by spectroscopic methods. This carbene complex reacted with siloxydienes in a [4 + 1] cycloaddition manner to give cyclopentene derivatives. It is noteworthy that this reaction proceeds with a catalytic amount of copper through in situ generation of a Fischer-type copper–siloxycarbene complex intermediate.

Catalytic application of sulfamic acid-functionalized magnetic Fe3O4nanoparticles (SA-MNPs) for protection of aromatic carbonyl compounds and alcohols: Experimental and theoretical studies

Protection techniques of functional groups within the structure of organic compounds are important synthetic methods against unwanted attacks from various reagents during synthetic sequences. Acetal and thioacetal groups are well known as protective funct