62067-18-9

Upstream product

• 14690-00-7 2-O-benzylglycerol 
• 127-08-2 potassium acetate 
• 105409-38-9 1,3-di-O-acetyl-2-O-benzylglycerol 
• 6946-10-7 1,3-diacetoxyacetone 
• 100-44-7 benzyl chloride 
• 114838-37-8 (((2-(benzyloxy)propane-1,3-diyl)bis(oxy))bis(methanetetrayl))hexabenzene 
• 64-19-7 acetic acid 
• 141-78-6 ethyl acetate 
• 100-39-0 benzyl bromide 

Downstream Products

• 126777-88-6 1,5-anhydro-2,3,6-tri-O-benzyl-4-O-(2′,3′,4′,6′-tetra-O-benzyl-β-D-galactopyranosyl)-D-arabino-hex-1-enitol 
• 126777-87-5 3-O-acetyl-2-O-benzyl-1-O-(2,3,6,2',3',4',6'-hepta-O-benzyl-α-lactosyl)-(R,S)-glycerol 
• 126777-89-7 2-O-benzyl-1-O-(2,3,6,2',3',4',6'-hepta-O-benzyl-α-lactosyl)-(R,S)-glycerol 

Relevant academic research and scientific papers

Selective Monoacetylation of Symmetrical Diols and Selective Monodeacetylation of Symmetrical Diacetates Using HY-Zeolite as Reusable Heterogeneous Catalyst

HY-Zeolite has been found to be an efficient and reusable catalyst for selective monoacetylation of symmetrical diols and selective monodeacetylation of symmetrical diacetates to form the products in high yields.

3-Acyloxy-2-phenalkylpropyl amides and esters of homovanillic acid as novel vanilloid receptor agonists

A series of 3-acyloxy-2-phenalkylpropyl amides and esters of homovanillic acid were designed and synthesized as vanilloid receptor agonists containing the three principal pharmacophores of resiniferatoxin. Amide analogues 23, 5 and 11 were found to be potent agonists in vanilloid receptor assay both for ligand binding and for activation.

Enzymatic enantioselective ester hydrolysis by carboxylesterase NP

The enzymatic hydrolysis of a series of carboxylic esters by carboxylesterase NP has been investigated in order to determine the scope and limitations of this enzyme. 2-Substituted propionates were hydrolyzed with high enantioselectivity when an aromatic moiety was part of the 2-substituent.Enantioselective hydrolysis could be accomplished with several 2-arypropionates, 2-(aryloxy)propionates and N-arylalanine esters.The propionate esters yielded propionic acids as (S) enantiomers, whereas the alanine esters yielded the (R) enantiomers.Without a 2-aryl substituent, the enzymatic hydrolysis of the propionates occurred at a lower rate without acceptable enantioselectivity.In addition to 2-substituted propionates, only a few other esters were hydrolyzed with high enantioselectivity by carboxylesterase NP, such as some prochiral disubstituted malonates. 1-Phenylethylacetate was the only substrate with chirality in the alcohol part of the ester that was found to be hydrolyzed enantioselectively.Carboxylesterase NP proved to be a powerful enzyme for kinetic resolution of propionate esters with an aromatic ring containing a 2-substituent.

SYNTHESIS AND CHARACTERIZATION OF 1-O-α-LACTOSYL-(R,S)-GLYCEROLS AND 1-O-α-LACTOSYL-3-O-β-LACTOSYL-(R,S)-GLYCEROLS

Coupling of 2,3,6,2',3',4',6'-hepta-O-benzyl-α-lactosyl bromide with an equimolar amount of 1-O-acetyl-2-O-benzyl-(R,S)-glycerols in the presence of tetraethylammonium bromide and 4 Angstroem molecular sieves in 1,2-dichloroethane afforded 3-O-acetyl-2-O-