62120-85-8Relevant articles and documents
Design and synthesis of 6-substituted amino-4-oxa-1-azabicyclo[3,2,0]heptan-7-one derivatives as cysteine proteases inhibitors
Zhou, Nian E.,Guo, Deqi,Kaleta, Jadwiga,Purisima, Enrico,Menard, Robert,Micetich, Ronald G.,Singh, Rajeshwar
, p. 3413 - 3415 (2002)
A series of 6-substituted amino-4-oxa-1-azabicyclo[3,2,0]heptan-7-one compounds was designed and synthesized as a new class of inhibitors for cysteine proteases cathepsins B, L, K, and S. One compound (5S,6S)-6-(N-benzyloxycarbonyl-L-phenylalanyl) amino-4
A Simple Method for Amide Formation from Protected Amino Acids and Peptides
Chen, Shui-Tein,Wu, Shih-Hsiung,Wang, Kung-Tsung
, p. 37 - 38 (2007/10/02)
Amide formation from protected amino acids and peptides is directly and simply achieved by using 1-hydroxybenzotriazole as activating agent and treating the intermediate O-(benzotriazol-1-yl) derivative ("active ester") in situ with 25percent ammonium hydroxide solution.