Bioorganic and Medicinal Chemistry Letters p. 3413 - 3415 (2002)
Update date:2022-08-05
Topics:
Zhou, Nian E.
Guo, Deqi
Kaleta, Jadwiga
Purisima, Enrico
Menard, Robert
Micetich, Ronald G.
Singh, Rajeshwar
A series of 6-substituted amino-4-oxa-1-azabicyclo[3,2,0]heptan-7-one compounds was designed and synthesized as a new class of inhibitors for cysteine proteases cathepsins B, L, K, and S. One compound (5S,6S)-6-(N-benzyloxycarbonyl-L-phenylalanyl) amino-4
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