62208-67-7

Basic information

• Product Name: 3-AMINO-1-BENZOFURAN-2-CARBONITRILE
• Synonyms: 3-amino-1-benzofuran-2-carbonitrile(SALTDATA: FREE);3-AMino-benzofuran-2-carbonitrile
• CAS NO: 62208-67-7
• Molecular Formula: C₉H₆N₂O
• Molecular Weight: 158.16
• Mol File: 62208-67-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 149 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 347.3 °C at 760 mmHg
• Flash Point: 163.8 °C
• Appearance: /
• Density: 1.31 g/cm³
• Vapor Pressure: 5.45E-05mmHg at 25°C
• Refractive Index: 1.673
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -1.13±0.10(Predicted)
• CAS DataBase Reference: 3-AMINO-1-BENZOFURAN-2-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-1-BENZOFURAN-2-CARBONITRILE(62208-67-7)
• EPA Substance Registry System: 3-AMINO-1-BENZOFURAN-2-CARBONITRILE(62208-67-7)

Safety Data

• Hazardous Substances Data: 62208-67-7(Hazardous Substances Data)

Usage

General Description

3-Amino-1-benzofuran-2-carbonitrile is an organic compound with the chemical formula C9H6N2O. It is a light yellow to brown powder with a melting point of 247-250°C. This chemical is a benzofuran derivative, and it is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has also been studied for its potential biological and pharmacological activities, including its anti-inflammatory and anti-cancer properties. Additionally, 3-Amino-1-benzofuran-2-carbonitrile has shown potential as a fluorescent probe in biological imaging applications. Its versatility and potential applications make it an important chemical compound in various fields of science and industry.

InChI:InChI=1/C9H6N2O/c10-5-8-9(11)6-3-1-2-4-7(6)12-8/h1-4H,11H2

Upstream product

• 611-20-1 salicylonitrile 
• 590-17-0 cyanomethyl bromide 
• 107-14-2 chloroacetonitrile 
• 49615-99-8 (2-cyanophenoxy)acetonitrile 

Downstream Products

• 65023-81-6 N-phenylbenzofuro[3,2-d]pyrimidin-4-amine 
• 49679-19-8 4-Aminobenzofuro<3,2-d>pyrimidine 
• 74988-49-1 N-Benzo[4,5]furo[3,2-d]pyrimidin-4-yl-4-methyl-benzenesulfonamide 
• 74988-43-5 3-(4-Chloro-phenyl)-3H-benzo[4,5]furo[3,2-d]pyrimidin-4-ylideneamine 
• 74988-42-4 3-Phenyl-3H-benzo[4,5]furo[3,2-d]pyrimidin-4-ylideneamine 
• 65023-84-9 benzo[4,5]furo[3,2-d]pyrimidin-4-yl-(4-chloro-phenyl)-amine 
• 65023-77-0 4-Benzylaminobenzofuro<3,2-d>pyrimidine 
• 134221-91-3 4-(2-hydroxyethylamino)-2-phenylbenzofuro<3,2-d>pyrimidine 
• 134221-94-6 5-phenyl-2,3-dihydrobenzofuro<2,3-e>imidazo<1,2-c>pyrimidine 
• 134221-88-8 4-chloro-2-phenylbenzofuro<3,2-d>pyrimidine 
• 39786-40-8 4-chloro-2-methylbenzofuro<3,2-d>pyrimidine 

Relevant articles and documents

Efficient new synthesis of N-arylbenzo[b]furo[3,2-d]pyrimidin-4-amines and their benzo[b]thieno[3,2-d]pyrimidin-4-amine analogues via a microwave-assisted Dimroth rearrangement

A useful and rapid access to libraries of N-arylbenzo[b]furo[3,2-d] pyrimidin-4-amines (1) and their novel benzo[b]thieno[3,2-d]pyrimidin-4-amine analogues (2) was investigated for the first time. Title compounds were obtained via microwave-accelerated co

Benzothiophenes and benzofurans and antiallergic use thereof

Novel benzothiophene and benzofuran derivatives having antiallergic activity are described as well as a method of manufacture, pharmaceutical compositions, and methods of use therefor. The disclosure describes the use of derivatives for prevention of the release of mediators including histamine and leukotrienes from basophils and mast cells, and prevent respiratory burst in neutrophils providing activity useful in cardiovascular disorders as well as in antiinflammatory, psoriasis, and antimigraine treatment.