622369-38-4 Usage
Uses
Used in Pharmaceutical Research:
7-Fluoro-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile is used as a research compound for exploring its potential biological activities. The presence of various functional groups in its structure allows for the investigation of its anti-cancer, anti-inflammatory, and antimicrobial properties.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 7-Fluoro-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile is used as a starting material or a building block for the synthesis of new compounds with improved pharmacological properties. The fluoro and methoxy groups in 7-Fluoro-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile can be further modified to optimize its biological activity and selectivity.
Used in Drug Design and Development:
7-Fluoro-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile is utilized in drug design and development processes to create novel therapeutic agents with potential applications in various diseases and conditions. Its unique structure and functional groups make it a valuable candidate for the development of new drugs with enhanced efficacy and safety profiles.
Used in Chemical Synthesis:
7-Fluoro-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile serves as an intermediate in the synthesis of other quinoline-based compounds. Its versatile structure allows for further functionalization and modification, enabling the preparation of a wide range of quinoline derivatives with diverse applications in various fields, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 622369-38-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,2,2,3,6 and 9 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 622369-38:
(8*6)+(7*2)+(6*2)+(5*3)+(4*6)+(3*9)+(2*3)+(1*8)=154
154 % 10 = 4
So 622369-38-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H7FN2O2/c1-16-10-2-7-9(3-8(10)12)14-5-6(4-13)11(7)15/h2-3,5H,1H3,(H,14,15)
622369-38-4Relevant academic research and scientific papers
3-Cyanoquinolines, Methods for Preparation and Use as Insulin-like Growth Factor Inhibitors
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Page/Page column 12-13, (2009/10/30)
Imidazole-substituted 4-anilino-3-cyanoquinolines are described, which selectively inhibit IFGR kinase activity and are useful for treating disorders associated with IGFR kinases.
4-ANILINO-3-QUINOLINECARBONITRILES FOR THE TREATMENT OF CHRONIC MYELOGENOUS LEUKEMIA (CML)
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Page/Page column 21-22, (2010/02/11)
Compounds of the formula (I): wherein: n is an integer from 0-3; X is N, CH; R is alkyl of 1 to 3 carbon atoms; R' is 2,4-diCl, 5-OMe in para, ortho, or meta position; 2,4-diCl in para position; 3,4,5-tri-OMe in para position; 2-Cl, 5-OMe in para position
7-Alkoxy-4-phenylamino-3-quinolinecarbonitriles as Dual Inhibitors of Src and Abl Kinases
Boschelli, Diane H.,Wang, Yanong D.,Johnson, Steve,Wu, Biqi,Ye, Fei,Barrios Sosa, Ana Carolina,Golas, Jennifer M.,Boschelli, Frank
, p. 1599 - 1601 (2007/10/03)
We previously reported that several 7-alkoxy-4-phenylamino-3-quinolinecarbonitriles were potent inhibitors of Src kinase activity. We disclose here a new highly efficient and versatile route to these compounds, which are also potent inhibitors of Abl kina
Process for the preparation of 7-substituted-3 quinolinecarbonitriles
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Page/Page column 11, (2010/11/30)
There is provided a process for the preparation of 7-substituted-3-quinolinecarbonitriles and intermediates useful in a process to prepare 7-substituted-3-quinolinecarbonitriles and pharmaceutically acceptable salts is described. Where 7-fluoro-4-oxo-1,4-
