622864-48-6

Basic information

• Product Name: Boronic acid, (3-hydroxy-4-methoxyphenyl)- (9CI)
• Synonyms: Boronic acid, (3-hydroxy-4-methoxyphenyl)- (9CI);3-Hydroxy-4-methoxybenzeneboronic acid
• CAS NO: 622864-48-6
• Molecular Formula: C₇H₉BO₄
• Molecular Weight: 167.95496
• Product Categories: BORONICACID
• Mol File: 622864-48-6.mol

Chemical Properties

• Melting Point: 221 °C
• Boiling Point: 380.5±52.0 °C(Predicted)
• Appearance: /
• Density: 1.32±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 8.63±0.10(Predicted)
• CAS DataBase Reference: Boronic acid, (3-hydroxy-4-methoxyphenyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Boronic acid, (3-hydroxy-4-methoxyphenyl)- (9CI)(622864-48-6)
• EPA Substance Registry System: Boronic acid, (3-hydroxy-4-methoxyphenyl)- (9CI)(622864-48-6)

Safety Data

• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 622864-48-6(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
Boronic acid, (3-hydroxy-4-methoxyphenyl)(9CI) is used as a key intermediate in various chemical reactions, particularly in Suzuki coupling reactions for the synthesis of organic compounds. Its unique structure allows for the formation of stable carbon-carbon bonds, facilitating the creation of complex organic molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, boronic acid, (3-hydroxy-4-methoxyphenyl)(9CI) is studied for its potential applications as inhibitors of enzymes and in the development of new drugs. Its specific properties enable it to interact with biological targets, offering opportunities for the design of novel therapeutic agents.
Used in Pharmaceutical Industry:
Boronic acid, (3-hydroxy-4-methoxyphenyl)(9CI) is used as a building block in the pharmaceutical industry for the synthesis of various drug candidates. Its versatility and reactivity make it an important component in the development of new pharmaceuticals with improved efficacy and selectivity.
Used in Biotechnological Applications:
Boronic acid, (3-hydroxy-4-methoxyphenyl)(9CI) also finds applications in biotechnology, where it can be employed in the design of biosensors, drug delivery systems, and other biocompatible materials. Its ability to form stable complexes with biological molecules makes it a promising candidate for various biotechnological applications.

Upstream product

• 243990-54-7 (3-(benzyloxy)-4-methoxyphenyl)boronic acid 
• 78504-28-6 2-Benzyloxy-4-bromo-1-methoxybenzene 

Downstream Products

• 1292297-05-2 4-(3-hydroxy-4-methoxyphenyl)-6-methoxy-2H-chromen-2-one 
• 1292297-06-3 4-(3'-hydroxy-4'-methoxyphenyl)-5,6-dimethoxycoumarin 
• 1292297-03-0 4-(3-hydroxy-4-methoxyphenyl)-2H-chromen-2-one 
• 1292297-04-1 4-(3'-hydroxy-4'-methoxyphenyl)-5-methoxycoumarin 
• 1292297-07-4 4-(3'-hydroxy-4'-methoxyphenyl)-6,7-dimethoxycoumarin 
• 117048-62-1 combrestatin A₄ 
• 1444006-29-4 1-(3-hydroxy-4-methoxyphenyl)-6-(3,4,5-trimethoxyphenyl)pyridin-2(1H)-one 
• 1444006-16-9 6-(3-hydroxy-4-methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)pyridin-2(1H)-one 
• 1592413-80-3 5-(6-(2,4-dimethoxyphenyl)pyridine-2-yl)-2-methoxyphenol 
• 1592413-81-4 2-methoxy-5-(6-(3,4,5-trimethoxyphenyl)pyridine-2-yl)phenol 
• 61243-84-3 C₁₈H₁₆O₆ 

Relevant articles and documents

Synthesis and biological evaluation of 4-arylcoumarin analogues of combretastatins. Part 2

Figure Presented. A series of A-ring variously methoxylated 4-(3-hydroxy-4-methoxyphenyl)coumarins related to combretastatin A-4 was prepared by cross-coupling reactions. Cytotoxicity studies indicated a potent activity against HBL100 cell line. Substitut