62353-39-3Relevant academic research and scientific papers
General 5-Halomethyl Isoxazoline Synthesis Enabled by Copper-Catalyzed Oxyhalogenation of Alkenes
Li, Xiaoqing,Ding, Yu,Qian, Lijie,Gao, Yang,Wang, Xinqiang,Yan, Xinhuan,Xu, Xiangsheng
, p. 12656 - 12663 (2019/10/14)
A general and efficient oxyhalogenation of unsaturated ketoximes has been achieved through copper catalysis with diethyl bromomalonate, N-chlorosuccinimide, and N-iodosuccinimide, yielding 5-chloromethyl, 5-bromomethyl, and 5-iodomethyl isoxazolines in go
Oxime-mediated oxychlorination and oxybromination of unactivated olefins
Dong, Kui-Yong,Qin, Hai-Tao,Liu, Feng,Zhu, Chen
, p. 1419 - 1422 (2015/03/04)
An oxime-mediated oxychlorination and oxybromination of unactivated olefins relying on palladium catalysis has been developed. A wide range of chlorinated and brominated isoxazolines has been synthesized in moderate to good yields. To demonstrate the value of the method, the brominated isoxazoline has been further converted to other useful synthetic feedstock.
