624-82-8Relevant academic research and scientific papers
Survey Reactivity of Some Substituted Quinazolinones with Pentafluoro(chloro)pyridine
Ranjbar-Karimi, Reza,Davodian, Tayebeh,Mehrabi, Hossein
, p. 475 - 480 (2017/12/28)
A new series of 4-hetroaryl substituted quinazolines were designed and synthesized by the reaction of pentafluoro(chloro)pyridine and 2-substituted quinazolinone. The aromatic nucleophilic substitution of pentafluoro(chloro)pyridine with quinazolinone occurs at the 4-position of pyridine ring by the oxygen site (O-centered nucleophile) of quinazolinone. The structures of all the compounds were confirmed by IR, 1H NMR, 19F NMR, and 13C NMR spectroscopy as well as elemental analysis.
Novel process for the preparation of pyrazolopyrimidinones
-
, (2008/06/13)
There is provided a process for the production a compound of general formula I: wherein A, R1, R2, R3 and R4 have meanings given in the description, which process comprises the reaction of a compound of formula II, wherein Rx is a group substitutable by an aminopyrazole, with a compound of general formula III
