63726-68-1

Basic information

• Product Name: Benzeneacetaldehyde, a-acetyl-
• CAS NO: 63726-68-1
• Molecular Formula: C10H10O2
• Molecular Weight: 162.188
• Mol File: 63726-68-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzeneacetaldehyde, a-acetyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetaldehyde, a-acetyl-(63726-68-1)
• EPA Substance Registry System: Benzeneacetaldehyde, a-acetyl-(63726-68-1)

Safety Data

• Hazardous Substances Data: 63726-68-1(Hazardous Substances Data)

Usage

General Description

Benzeneacetaldehyde, also known as a-acetylbenzaldehyde, is a colorless liquid organic compound with a distinct almond-like odor. It is commonly used as a flavoring agent in the food industry and as a fragrance ingredient in cosmetics and personal care products. Benzeneacetaldehyde is also used in the chemical synthesis of various pharmaceuticals and as an intermediate in the production of other organic compounds. Additionally, it has been studied for its potential antimicrobial and antioxidant properties. However, benzeneacetaldehyde is considered toxic and potentially harmful to human health, with exposure to high levels posing health risks such as irritation to the respiratory system and skin. Therefore, safe handling and proper ventilation are necessary when using this chemical in any industrial or laboratory setting.

Upstream product

• 6249-79-2 1-(3-phenyloxiran-2-yl)ethanone 
• 1346254-67-8 [benzyl-((E)-3-oxo-2-phenylbut-1-enyl)amino]methylphosphonic acid diethyl ester 
• 103-79-7 1-phenyl-acetone 
• 109-94-4 formic acid ethyl ester 
• 107-31-3 Methyl formate 
• 6249-79-2 trans-2-acetyl-3-phenyloxirane 

Downstream Products

• 27913-51-5 1-phenyl-propane-1,2-dione-1-phenylhydrazone 
• 32123-84-5 3-phenylbut-3-en-2-one 
• 62559-37-9 1-Hydroxy-2-phenylbutan-3-one 
• 1666-96-2 3-phenylquinoline 
• 4468-48-8 1-phenyl-1-cyanopropan-2-one 
• 79815-54-6 anhydro-2,6-diphenyl-1-hydroxy-5-methyl-3-oxopyrazolo<1,2-a>pyrazolium hydroxide 
• 13788-84-6 3-Methyl-4-phenyl-1H-pyrazole 
• 23253-49-8 5-methyl-4-phenylisoxazole 

Relevant articles and documents

Metal-free, one-pot, sequential protocol for transforming ,-epoxy ketones to -hydroxy ketones and -methylene ketones

A new sequential, one-pot protocol for transforming 1,3-disubstituted 2,3-epoxy ketones to β;-hydroxy ketones and α-methylene ketones has been developed. Reaction of epoxy ketones with boron trifluoride etherate (BF3·OEt2) generates the cationic intermediates by regioselective epoxide ring opening and an acyl shift. Then, a treatment of these cations with 2-aryl-1,3-dimethylbenzimidazolines (DMBIH) results in formation of 1,2-disubstituted 3-hydroxy ketones. DMBIH serves as a hydride donor in the second step of this process. Finally, the β;-hydroxy ketones can be converted to 1,2-disubstituted 2-methylene ketones by treatment with methanesulfonic acid or a combination of methanesulfonyl chloride and triethylamine. Importantly, the sequential steps involved in formation of the α-methylene ketone products can be carried out in one pot.

Highly chemo- and regioselective rearrangement of α,β-epoxy ketones to 1,3-dicarbonyl compounds in 5 mol dm-3 lithium perchlorate-diethyl ether medium

Epoxides from α,β-unsaturated ketones undergo highly chemo- and regioselective rearrangement to 1,3-dicarbonyl compounds in 5 mol dm-3 lithium perchlorate-diethyl ether medium by a 1,2-migration of the carbonyl group at ambient conditions. The Royal Society of Chemistry 1999.