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62669-70-9

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Rhodamine 123
Cas No: 62669-70-9
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
High purity 62669-70-9 3,6-diamino-9-[2-(methoxycarbonyl)phenyl]xanthylium chloride
Cas No: 62669-70-9
USD $ 100.0-500.0 / Gram 1 Gram 99999 Gram/Year Hangzhou Dingyan Chem Co., Ltd Contact Supplier
2-(6-Amino-3-imino-3H-xanthen-9-yl)-benzoic acid methyl ester hydrochloride
Cas No: 62669-70-9
No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier
Large Stock 99.0% 3,6-diamino-9-[2-(methoxycarbonyl)phenyl]xanthylium chloride 62669-70-9 Producer
Cas No: 62669-70-9
USD $ 0.1-0.1 / Gram 1 Gram 100 Metric Ton/Year Xi'an Xszo Chem Co., Ltd. Contact Supplier
Pharmaceutical Grade CAS 62669-70-9 with competitive price
Cas No: 62669-70-9
USD $ 139.0-210.0 / Kilogram 1 Kilogram 1000 Kilogram/Day Zhuozhou Wenxi import and Export Co., Ltd Contact Supplier
BLOOM TECH Advanced API/Technology support Rhodamine 123 CAS 62669-70-9
Cas No: 62669-70-9
No Data 1 Gram 3 Metric Ton/Month Shaanxi BLOOM TECH Co.,Ltd Contact Supplier
Xanthylium,3,6-diamino-9-[2-(methoxycarbonyl)phenyl]-, chloride (1:1)
Cas No: 62669-70-9
No Data No Data 10000 Metric Ton/Month Henan Wentao Chemical Product Co., Ltd. Contact Supplier
Rhodamine 123
Cas No: 62669-70-9
USD $ 76.0-85.0 / Kilogram 1 Kilogram 100 Metric Ton/Month Baoji Guokang Healthchem co.,ltd Contact Supplier
Xanthylium,3,6-diamino-9-[2-(methoxycarbonyl)phenyl]-, chloride (1:1)
Cas No: 62669-70-9
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JSY Trade 62669-70-9
Cas No: 62669-70-9
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62669-70-9 Usage

Uses

Fluorescent dye most commonly used as functional reporter in flow cytometry.

Uses

Rhodamine-123 lycoprotein (P-gp) functional efflux activity in vivo. Rhodamine-123 PE-Cy5 and AMCA (7-amino-4-methylcoumarin-3-acetic acid).

Uses

Rhodamine derivative, a fluoresent dye-labeled compound.

Chemical Properties

red-brown to brown or dark green powder

Uses

Useful as a laser dye and to have selective cell growth effects. Mitochondrial specific fluorescent dye and substrate for P-glycoprotein.
InChI:InChI=1/C21H17N2O3.ClH/c1-25-21(24)15-5-3-2-4-14(15)20-16-8-6-12(22)10-18(16)26-19-11-13(23)7-9-17(19)20;/h2-11H,22-23H2,1H3;1H/q+1;/p-1

62669-70-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name rhodamine 123

1.2 Other means of identification

Product number -
Other names RHODAMINE 123,PURE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:62669-70-9 SDS

62669-70-9Synthetic route

methanol
67-56-1

methanol

rhodamine 110 chloride
13558-31-1

rhodamine 110 chloride

rhodamin 123
62669-70-9

rhodamin 123

Conditions
ConditionsYield
With hydrogenchloride 1.) reflux, 6 h, 2.) RT, overnight;
With sulfuric acid at 50℃; Esterification;
With acetyl chloride at 50℃; Fischer esterification;
Dihydrorhodamine 123
109244-58-8

Dihydrorhodamine 123

rhodamin 123
62669-70-9

rhodamin 123

Conditions
ConditionsYield
In acetone Electrochemical reaction;
rhodamin 123
62669-70-9

rhodamin 123

2'-(6-amino-4,5-dibromo-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester hydrochloride

2'-(6-amino-4,5-dibromo-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester hydrochloride

Conditions
ConditionsYield
With bromine In ethanol for 73.5h; Ambient temperature;100%
potassium tetrachloroplatinate(II)
10025-99-7

potassium tetrachloroplatinate(II)

rhodamin 123
62669-70-9

rhodamin 123

bis(rhodamine 123)tetrachloroplatinate(II) tetrahydrate
104114-29-6

bis(rhodamine 123)tetrachloroplatinate(II) tetrahydrate

Conditions
ConditionsYield
In water stirring (30 min, pptn.); filtration, washing (H2O, 1N HCl, EtOH, ether), drying (vac.); elem. anal.;78%
rhodamin 123
62669-70-9

rhodamin 123

2-(6-Amino-3-imino-2,7-diiodo-3H-xanthen-9-yl)-benzoic acid methyl ester; hydrochloride

2-(6-Amino-3-imino-2,7-diiodo-3H-xanthen-9-yl)-benzoic acid methyl ester; hydrochloride

Conditions
ConditionsYield
With Iodine monochloride In tetrahydrofuran for 5h; Ambient temperature;76%
rhodamin 123
62669-70-9

rhodamin 123

2-(6-Amino-2,7-dibromo-3-imino-3H-xanthen-9-yl)-benzoic acid methyl ester; hydrochloride

2-(6-Amino-2,7-dibromo-3-imino-3H-xanthen-9-yl)-benzoic acid methyl ester; hydrochloride

Conditions
ConditionsYield
With bromine In ethanol at -40℃; for 2h;76%
rhodamin 123
62669-70-9

rhodamin 123

2-(6-Amino-2-bromo-3-imino-3H-xanthen-9-yl)-benzoic acid methyl ester; hydrochloride

2-(6-Amino-2-bromo-3-imino-3H-xanthen-9-yl)-benzoic acid methyl ester; hydrochloride

Conditions
ConditionsYield
With bromine In ethanol for 1h;62%
rhodamin 123
62669-70-9

rhodamin 123

2-(6-Amino-2,4,5,7-tetrabromo-3-imino-3H-xanthen-9-yl)-benzoic acid methyl ester; hydrochloride

2-(6-Amino-2,4,5,7-tetrabromo-3-imino-3H-xanthen-9-yl)-benzoic acid methyl ester; hydrochloride

Conditions
ConditionsYield
With bromine In ethanol for 2h; Ambient temperature;56.45%
rhodamin 123
62669-70-9

rhodamin 123

2-(6-Amino-3-imino-2-iodo-3H-xanthen-9-yl)-benzoic acid methyl ester; hydrochloride

2-(6-Amino-3-imino-2-iodo-3H-xanthen-9-yl)-benzoic acid methyl ester; hydrochloride

Conditions
ConditionsYield
With Iodine monochloride In tetrahydrofuran for 5h; Ambient temperature;34%
rhodamin 123
62669-70-9

rhodamin 123

Dihydrorhodamine 123
109244-58-8

Dihydrorhodamine 123

Conditions
ConditionsYield
With sodium tetrahydroborate In dichloromethane; water for 1h;
rhodamin 123
62669-70-9

rhodamin 123

[125]I-methyl o-(2-iodo-6-amino-3-imino-3H-xanthen-9-yl)benzoate monochloride

[125]I-methyl o-(2-iodo-6-amino-3-imino-3H-xanthen-9-yl)benzoate monochloride

Conditions
ConditionsYield
With peracetic acid; sodium (¹²⁵I)iodide; [131I]-sodium iodide; acetate buffer; sodium acetate for 1h; Ambient temperature; Yield given;
rhodamin 123
62669-70-9

rhodamin 123

2-(6-Amino-3-imino-3H-xanthen-9-yl)-benzoic acid methyl ester; compound with perchloric acid

2-(6-Amino-3-imino-3H-xanthen-9-yl)-benzoic acid methyl ester; compound with perchloric acid

Conditions
ConditionsYield
With sodium perchlorate In water cation exchange;
p-Aminophenethylamine
13472-00-9

p-Aminophenethylamine

rhodamin 123
62669-70-9

rhodamin 123

2-(6-amino-3-imino-3H-xanthen-9-yl)-N-[2-(4-amino-phenyl)-ethyl]-benzamide

2-(6-amino-3-imino-3H-xanthen-9-yl)-N-[2-(4-amino-phenyl)-ethyl]-benzamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 12h; amidation;
4-Aminobutanol
13325-10-5

4-Aminobutanol

rhodamin 123
62669-70-9

rhodamin 123

2-(6-amino-3-imino-3H-xanthen-9-yl)-N-(4-hydroxy-butyl)-benzamide

2-(6-amino-3-imino-3H-xanthen-9-yl)-N-(4-hydroxy-butyl)-benzamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 12h; amidation;
rhodamin 123
62669-70-9

rhodamin 123

17-(2-amino-ethylamino)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-ol

17-(2-amino-ethylamino)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-ol

2-(6-amino-3-imino-3H-xanthen-9-yl)-N-[2-(3-hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-ylamino)-ethyl]-benzamide

2-(6-amino-3-imino-3H-xanthen-9-yl)-N-[2-(3-hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-ylamino)-ethyl]-benzamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 96h; amidation;
rhodamin 123
62669-70-9

rhodamin 123

2-{6-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[(Z)-9H-fluoren-9-ylmethoxycarbonylimino]-2-iodo-3H-xanthen-9-yl}-benzoic acid methyl ester

2-{6-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[(Z)-9H-fluoren-9-ylmethoxycarbonylimino]-2-iodo-3H-xanthen-9-yl}-benzoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 34 percent / ICl / tetrahydrofuran / 5 h / Ambient temperature
2: 70 percent / diisopropylethylamine / CH2Cl2 / 4 h
View Scheme
rhodamin 123
62669-70-9

rhodamin 123

2-[6-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-imino-2-iodo-3H-xanthen-9-yl]-benzoic acid methyl ester; hydrochloride

2-[6-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-imino-2-iodo-3H-xanthen-9-yl]-benzoic acid methyl ester; hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 34 percent / ICl / tetrahydrofuran / 5 h / Ambient temperature
2: diisopropylethylamine / CH2Cl2 / 4 h
View Scheme
rhodamin 123
62669-70-9

rhodamin 123

4'-iododihydrorhodamine 123
109282-63-5

4'-iododihydrorhodamine 123

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaBH4 / CH2Cl2; H2O / 1 h
2: 11 percent / NaI, N-chlorosuccinimide (NClS), 0.2 M NH4OAc / methanol; CH2Cl2; CCl4 / 1 h / 0 - 20 °C
View Scheme
Multi-step reaction with 2 steps
1: NaBH4 / CH2Cl2; H2O / 1 h
2: 5 percent / NaI, N-chlorosuccinimide (NClS), 0.2 M NH4OAc / methanol; CH2Cl2; CCl4 / 1 h / Ambient temperature
View Scheme
rhodamin 123
62669-70-9

rhodamin 123

2'-iododihydrorhodamine 123
109244-59-9

2'-iododihydrorhodamine 123

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaBH4 / CH2Cl2; H2O / 1 h
2: 21 percent / NaI, N-chlorosuccinimide (NClS), 0.2 M NH4OAc / methanol; CH2Cl2; CCl4 / 1 h / 0 - 20 °C
View Scheme
Multi-step reaction with 2 steps
1: NaBH4 / CH2Cl2; H2O / 1 h
2: 44 percent / NaI, N-chlorosuccinimide (NClS), 0.2 M NH4OAc / methanol; CH2Cl2; CCl4 / 1 h / Ambient temperature
View Scheme
rhodamin 123
62669-70-9

rhodamin 123

4',7'-diiododihydrorhodamine 123
109244-61-3

4',7'-diiododihydrorhodamine 123

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaBH4 / CH2Cl2; H2O / 1 h
2: 12 percent / NaI, N-chlorosuccinimide (NClS), 0.2 M NH4OAc / methanol; CH2Cl2; CCl4 / 1 h / 0 - 20 °C
View Scheme
Multi-step reaction with 2 steps
1: NaBH4 / CH2Cl2; H2O / 1 h
2: 23 percent / NaI, N-chlorosuccinimide (NClS), 0.2 M NH4OAc / CH2Cl2; CCl4 / 1 h / Ambient temperature
View Scheme
rhodamin 123
62669-70-9

rhodamin 123

2',7'-diiododihydrorhodamine 123
109244-60-2

2',7'-diiododihydrorhodamine 123

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaBH4 / CH2Cl2; H2O / 1 h
2: 17 percent / NaI, N-chlorosuccinimide (NClS), 0.2 M NH4OAc / methanol; CH2Cl2; CCl4 / 1 h / 0 - 20 °C
View Scheme
Multi-step reaction with 2 steps
1: NaBH4 / CH2Cl2; H2O / 1 h
2: 9 percent / NaI, N-chlorosuccinimide (NClS), 0.2 M NH4OAc / methanol; CH2Cl2; CCl4 / 1 h / Ambient temperature
View Scheme
Multi-step reaction with 2 steps
1: NaBH4 / CH2Cl2; H2O / 1 h
2: 25 percent / NaI, N-chlorosuccinimide (NClS), 0.2 M NH4OAc / CH2Cl2; CCl4 / 1 h / Ambient temperature
View Scheme
rhodamin 123
62669-70-9

rhodamin 123

2',4',7'-triiododihydrorhodamine 123
109244-62-4

2',4',7'-triiododihydrorhodamine 123

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaBH4 / CH2Cl2; H2O / 1 h
2: 7 percent / NaI, N-chlorosuccinimide (NClS), 0.2 M NH4OAc / CH2Cl2; CCl4 / 1 h / Ambient temperature
View Scheme
rhodamin 123
62669-70-9

rhodamin 123

Cycloheximide
66-81-9

Cycloheximide

C36H39N3O6

C36H39N3O6

Conditions
ConditionsYield
With sodium cyanoborohydride; acetic acid In methanol; water at 37℃; for 16h;
rhodamin 123
62669-70-9

rhodamin 123

β‐cyclodextrin
7585-39-9

β‐cyclodextrin

C42H70O35*C21H16N2O3*ClH

C42H70O35*C21H16N2O3*ClH

Conditions
ConditionsYield
In water at 14.84℃; Thermodynamic data; Temperature;
heptakis(2,6-di-O-methyl)cyclomaltoheptaose
51166-71-3

heptakis(2,6-di-O-methyl)cyclomaltoheptaose

rhodamin 123
62669-70-9

rhodamin 123

C56H98O35*C21H16N2O3*ClH

C56H98O35*C21H16N2O3*ClH

Conditions
ConditionsYield
In water at 14.84℃; Thermodynamic data; Temperature;
rhodamin 123
62669-70-9

rhodamin 123

lithium bis((pentafluoroethyl)sulfonyl)amide

lithium bis((pentafluoroethyl)sulfonyl)amide

C21H16N2O3*C4F10NO4S2(1-)*H(1+)

C21H16N2O3*C4F10NO4S2(1-)*H(1+)

Conditions
ConditionsYield
In dichloromethane; water at 20℃; for 48h;
sodium tetraphenyl borate
143-66-8

sodium tetraphenyl borate

rhodamin 123
62669-70-9

rhodamin 123

C21H16N2O3*C24H20B(1-)*H(1+)

C21H16N2O3*C24H20B(1-)*H(1+)

Conditions
ConditionsYield
In dichloromethane; water at 20℃; for 48h;
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