90246-52-9Relevant academic research and scientific papers
Benzisoxazole carboxylic acids
-
, (2008/06/13)
Described are compounds of the formula STR1 wherein X is hydrogen, loweralkyl, halo, loweralkoxy or trifluoromethyl, and Z is hydrogen, loweralkyl, halo, hydroxy or alkoxy, or compounds of the formula STR2 wherein X' and Y' may be the same or different an
Benzisoxazole carboxylic acids
-
, (2008/06/13)
Described are compounds of the formula STR1 wherein X is hydrogen, loweralkyl, halo, loweralkoxy or trifluoromethyl, and Z is hydrogen, loweralkyl, halo, hydroxy or alkoxy, or compounds of the formula STR2 wherein X' and Y' may be the same or different an
Substituted 5,6-dihydrofuro[3,2-f]-1,2-benzisoxazole-6-carboxylic acids: High-ceiling diuretics with uricosuric activity
Plattner,Fung,Parks,et al.
, p. 1016 - 1026 (2007/10/02)
A series of substituted 5,6-dihydrofuro[3,2-f]-1,2-benzisoxazoles was prepared and evaluated for their saluretic and uricosuric properties. Pharmacological evaluation of the title compounds was carried out in mice, rats, dogs, and monkeys. The diuretic/sa
(Acylaryloxy)acetic Acid Diuretics. 3. 2,3-Dihydro-5-acyl-2-benzofurancarboxylic Acids, a New Class of Uricosuric Diuretics
Hoffman, William F.,Woltersdorf, Otto W.,Novello, Frederick C.,Cragoe, Edward J,Spinger, James P.,et al.
, p. 865 - 873 (2007/10/02)
The discovery that dihydroethacrynic acid and other (4-acylphenoxy)acetic acids possessed modest but significant uricosuric and diuretic activity prompted our investigation of the related 2,3-dihydro-5-acyl-2-benzofurancarboxylic acids.Synthetic routes to
2,3-Dihydro-6,7-disubstituted-5-acyl benzofuran-2-carboxylic acids
-
, (2008/06/13)
2,3-Dihydro-6,7-disubstituted-5-(acyl)benzofuran-2-carboxylic acids, the pharmaceutically acceptable salt, ester and amide derivatives thereof and combinations of these compounds with antikaluretic agents are disclosed having diuretic-saluretic, uricosuri
