6279-91-0

Basic information

• Product Name: ethyl 2-oxo-1-propylcyclohexanecarboxylate
• CAS NO: 6279-91-0
• Molecular Formula: C₁₂H₂₀O₃
• Molecular Weight: 212.2854
• Mol File: 6279-91-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 288.7°C at 760 mmHg
• Flash Point: 121.9°C
• Density: 1.012g/cm³
• Vapor Pressure: 0.0023mmHg at 25°C
• Refractive Index: 1.458
• CAS DataBase Reference: ethyl 2-oxo-1-propylcyclohexanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-oxo-1-propylcyclohexanecarboxylate(6279-91-0)
• EPA Substance Registry System: ethyl 2-oxo-1-propylcyclohexanecarboxylate(6279-91-0)

Safety Data

• Hazardous Substances Data: 6279-91-0(Hazardous Substances Data)

Upstream product

• 101493-23-6 1-(3-Iodo-propyl)-2-oxo-cyclohexanecarboxylic acid ethyl ester 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 75-03-6 ethyl iodide 
• 107-08-4 1-iodo-propane 
• 2050-20-6 diethyl pimelate 
• 106-94-5 propyl bromide 
• 62547-81-3 1-(3-bromo-propyl)-2-oxo-cyclohexanecarboxylic acid ethyl ester 

Downstream Products

• 1138530-00-3 ethyl 2-methylene-1-propylcyclohexane carboxylate 
• 62664-67-9 1-Carboxy-2-propylcyclohexan-1-essigsaeure 
• 62664-66-8 Cyano-[2-propyl-cyclohex-(Z)-ylidene]-acetic acid ethyl ester 
• 96107-28-7 (Z)-2-Propyl-penta-2,4-dienoic acid ethyl ester 
• 94-65-5 2-(n-propyl)cyclohexanone 

Relevant articles and documents

Diastereoselectivity control of the radical carboazidation of substituted methylenecyclohexanes

A systematic study of the diastereoselectivity of the radical carboazidation of methylenecyclohexane derivatives is presented. Several substitution patterns leading to a high level of stereocontrol have been identified. Axial attack is the preferred reaction pathway for cyclohexyl radicals, and excellent stereoselectivities can be obtained by introducing an axial substitutent at position 2. In this case, a second equatorial substituent at position 2 may be tolerated without a large detrimental effect on the diastereoselectivity. Finally, a high level of equatorial attack is observed with a very bulky substituent at position 2.

Studies on diastereoselective reduction of cyclic β-ketoesters with boron hydrides. Part 4: The reductive profile of functionalized cyclohexanone derivatives

Reduction of 2-allyl-2-carboalkoxycyclohexanones (3d-f), 2-propyl-2-carboethoxycyclohexanone (3g) and 2-benzyl-2- carboethoxycyclohexanone (3h) with boron hydrides in the presence and absence of several chelating agents were studied. Molecular modeling studies using semiempirical PM3 method were performed in order to find a suitable explanation of the diastereoselection of ketone carbonyl faces during the reductive process, which yielded trans-2-allyl-2-carboethoxycyclohexanol (6e) and cis-2-allyl-2-carboethoxycyclohexanol (7e) in good diastereomeric excess by using inexpensive sodium and tetrabutylammonium borohydrides.

NOVEL FREE RADICAL RING-EXPANSION REACTIONS

A novel free radical initiated ring expansion of haloalkyl β-keto esters is described.Following alkylation of the β-keto ester with the appropriate dihalide, the resulting halide is treated at reflux with tri-n-butyltin hydride.Rearrangement to the homolo