62830-55-1

Basic information

• Product Name: (4-Iodophenyl)hydrazine hydrochloride
• Synonyms: 4-Iodophenylhydrazine, HCl
• CAS NO: 62830-55-1
• Molecular Formula: C₆H₇IN₂*ClH
• Molecular Weight: 270.49859
• Mol File: 62830-55-1.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: (4-Iodophenyl)hydrazine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Iodophenyl)hydrazine hydrochloride(62830-55-1)
• EPA Substance Registry System: (4-Iodophenyl)hydrazine hydrochloride(62830-55-1)

Safety Data

• Hazardous Substances Data: 62830-55-1(Hazardous Substances Data)

Usage

General Description

(4-Iodophenyl)hydrazine hydrochloride is a chemical compound consisting of a hydrazine derivative with a phenyl ring substituted with an iodine atom. It is typically found in the form of a hydrochloride salt. (4-Iodophenyl)hydrazine hydrochloride is often used in organic synthesis as a reagent for the preparation of various organic compounds. It has been studied for its potential applications in pharmaceuticals and agrochemicals due to its ability to undergo various chemical reactions leading to the formation of new compounds. Additionally, (4-Iodophenyl)hydrazine hydrochloride has been investigated for its potential antimicrobial and anticancer properties. However, as with any chemical, proper handling and precautions should be observed when working with this compound.

Upstream product

• 540-37-4 p-aminoiodobenzene 

Downstream Products

• 4241-66-1 4-Iodobenzenesulphonyl Fluoride 
• 624-38-4 para-diiodobenzene 
• 92475-01-9 1-(4-iodophenyl)-1,2,4-triazole-3,5-diamine 
• 861083-81-0 (4-iodophenyl)(4-methoxyphenyl)thioether 
• 79271-22-0 4-(4-Iodobenzoyl)morpholine 
• 405924-38-1 5-iodo-2,3-diphenyl-1H-indole 
• 936252-96-9 2-(3-(5-iodo-1-(p-toluenesulfonyl)indolyl)ethyloxy)adenosine 
• 936252-82-3 6-chloro-2-(3''-(5''-iodo-1''-(p-toluenesulfonyl)indolyl)ethyloxy)-3',4',5'-triacetyladenosine 
• 936252-64-1 5-iodo-3-(2-iodoethyl)-1-(p-toluenesulfonyl)indole 
• 540475-62-5 2'-(4-iodophenyl)-17α-(1-propyn-1-yl)-11β,17β-dihydroxy-androst-4-eno[3,2-c]pyrazole 
• 62830-30-2 3-Hydroxy-4-[(4-iodo-phenyl)-hydrazono]-2-isobutyl-4H-naphthalen-1-one 
• 62830-31-3 3-Hydroxy-4-[(4-iodo-phenyl)-hydrazono]-1-oxo-1,4-dihydro-naphthalene-2-carboxylic acid ethyl ester 
• 62830-28-8 2-Ethyl-3-hydroxy-4-[(4-iodo-phenyl)-hydrazono]-4H-naphthalen-1-one 
• 62830-29-9 2-Butyl-3-hydroxy-4-[(4-iodo-phenyl)-hydrazono]-4H-naphthalen-1-one 

Relevant articles and documents

Transition-Metal-Free Coupling of Polyfluorinated Arenes and Functionalized, Masked Aryl Nucleophiles

A chemoselective C(sp2)?C(sp2) coupling of sufficiently electron-deficient fluorinated arenes and functionalized N-aryl-N’-silyldiazenes as masked aryl nucleophiles is reported. The fluoride-promoted transformation involves the in situ generation of the aryl nucleophile decorated with various sensitive functional groups followed by a stepwise nucleophilic aromatic substitution (SNAr). These reactions typically proceed at room temperature within minutes. This catalytic process allows for the functionalization of both coupling partners, furnishing highly fluorinated biaryls in good yields.

AZEPINO-INDOLES AND OTHER HETEROCYCLES FOR TREATING BRAIN DISORDERS

The present invention provides azepino-indoles and other heterocycles and methods of using the compounds for treating brain disorders.

Regioselective synthesis of indoles via rhodium-catalyzed C-H activation directed by an in-situ generated redox-neutral group

A regioselective synthesis of indoles from arylhydrazine hydrochlorides with alkynes and diethyl ketone catalyzed by a rhodium complex is described. A possible mechanism involving an in-situ generated oxidizing directing group -N-Ni'CR1R2 assisted ortho-C-H activation and reductive elimination are proposed. The catalytic reaction is highly compatible with a wide range of functional arylhydrazines and alkynes. The reaction proceeds under mild reaction conditions and is atom-step economical.