63002-70-0Relevant articles and documents
Quinazolinone-schiff's base hybrids as phosphodiesterase 4b inhibitors with dual activity against COPD and lung cancer
Mansour, Mostafa A.,El-Saadi, Mohamed T.,Amin, Noha H.,Canzoneri, Joshua C.,Keeton, Adam B.,Piazza, Gary A.,Abdel-Rahman, Hamdy M.
, p. 4851 - 4866 (2020/12/25)
A series of thirty compounds of quinazolinone-Schiff's base hybrids were rationally designed, synthesized, and evaluated for their in vitro Phosphodiesterase 4B inhibition, anti-lung and anti-colon cancer activities. Compounds 9, 16, 23, 29, 30, 31, 32 an
Synthesis of some N-(4-oxo-2-sustitutedphenylquinazolin-3-(4H)-yl)-2-[(5- aryl-1,3.4-oxadiazol-2-yl) sulfanyl] acetamides as antitubercular agents
Rao, Gopal Krishna,Rajasekaran,Sanjay Pai
body text, p. 293 - 294 (2011/12/15)
A series of some N-(4-oxo-2-substituted phenylquinazolin-3-(4H)-yl)-2-[(5- aryl-1,3,4-oxadiazol-2-yl) sulfanyl] acetamides 5 were synthesized and characterized on the basis of IR, NMR and mass spectral data. The title compounds were subjected to in-vitro
A New Synthesis of 2-Aryl-3,4-dihydro-5H-1,3,4-benzotriazepin-5-ones
Reddy, Ch. K.,Reddy, P. S. N.,Ratnam, C. V.
, p. 902 - 904 (2007/10/02)
The reaction of 2-aryl-3,1-benzoxazine-4-ones (1) and hydrazine hydrate in refluxing xylene yields 2-aryl-3,4-dihydro-5H-1,3,4-benzotriazepin-5-ones in 55-74percent yield.In basic conditions this reaction, however, gives 2-aryl-3-aminoquinazolin-4(3H)-one