6315-60-2

Usage

Uses

Used in Pharmaceutical Industry:
N,N-Di-(beta-carboethoxyethyl)methylamine is used as a reagent in the synthesis of various pharmaceuticals, contributing to the development of new drugs and improving the efficiency of existing ones.
Used in Dye Industry:
In the dye industry, N,N-Di-(beta-carboethoxyethyl)methylamine is employed in the production of dyes, enhancing their color properties and stability.
Used in Surfactant Industry:
N,N-Di-(beta-carboethoxyethyl)methylamine is used as a reagent in the manufacturing of surfactants, which are essential in various applications such as detergents, cleaning agents, and personal care products.
Used in Corrosion Inhibitor Industry:
N,N-Di-(beta-carboethoxyethyl)methylamine is utilized in the production of corrosion inhibitors, which are crucial in protecting metal surfaces from corrosion and extending their service life.
Used as a Catalyst in Organic Synthesis:
N,N-Di-(beta-carboethoxyethyl)methylamine acts as a catalyst in reactions involving the formation of carbon-carbon and carbon-nitrogen bonds, facilitating the synthesis of various organic compounds and improving the overall efficiency of the process.

Upstream product

• 59154-46-0 ethyl ester of β-bromoisobutyric acid 
• 2213-08-3 ethyl 3-methylaminopropionate 
• 539-74-2 Ethyl 3-bromopropionate 
• 593-51-1 methylamine hydrochloride 
• 97-63-2 methyl methacrylate 
• 590-92-1 3-Bromopropionic acid 
• 74-89-5 methylamine 
• 140-88-5 ethyl acrylate 
• 64-17-5 ethanol 
• 292638-85-8 acrylic acid methyl ester 
• 623-71-2 ethyl 3-chloropropanoate 

Downstream Products

• 499-04-7 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid 
• 63-75-2 arecoline 
• 37673-66-8 4-hydroxy-1-methyl-piperidine-3-carboxylic acid ethyl ester 
• 716362-70-8 (+/-)-4c-hydroxy-1-methyl-piperidine-3r-carboxylic acid 
• 5570-77-4 4-chloro-1-methylpiperidine 
• 106-52-5 N-methyl-4-hydroxypiperidine 
• 1445-73-4 1-Methyl-4-piperidone 
• 52835-63-9 (3E,5E)-3,5-dibenzylidene-1-methylpiperidin-4-one 
• 97762-23-7 4-diphenyl acetoxy N-methyl piperidine 
• 67288-79-3 3,5-bis-(2-chloro-benzylidene)-1-methyl-piperidin-4-one 
• 2167-01-3 1-methyl-3,5-bis-[1]naphthylmethylene-piperidin-4-one 
• 52835-56-0 (+/-)-6-((E)-benzylidene)-2,8-dimethyl-10t-phenyl-(10at)-1,2,3,4,6,7,8,9,10,10a-decahydro-pyrano[3,2-c;5,6-c']dipyridin-4ar-ol 
• 857237-28-6 3,5-dibenzyl-1-methyl-piperidin-4-ol 
• 111441-23-7 5-methyl-1,2-diphenyl-1,2,4,5,6,7-hexahydro-pyrazolo[4,3-c]pyridin-3-one 

Relevant academic research and scientific papers

DIMER COMPOUNDS, AND USE IN BINDING TOXIC REPEATS OF RNA

Provided herein are compounds and methods for modulating abnormal repeat expansions of gene sequences. More particularly, provided are dimeric inhibitors of RNA and the uses of such inhibitors in regulating nucleotide repeat expansions, e.g., to treat Myotonic Dystrophy Type 1 (DM1), Myotonic Dystrophy Type 2 (DM2), Fuchs dystrophy, Huntington Disease, Amyotrophic Lateral Sclerosis, or Frontotemporal Dementia.

Synthesis and antiproliferative activity of cyclic arylidene ketones: a direct comparison of monobenzylidene and dibenzylidene derivatives

Abstract To give further insight into the influence of the structural modifications of enones and dienones on their antiproliferative properties, 25 derivatives of enones: (E)-2-benzylidene-1-cyclohexanones, (E)-2-benzylidene-1-tetralones, (E)-2-benzylidene-1-indanone, and dienones: (E,E)-2,5- or 2,6-dibenzylidene-1-cyclanones, (E,E)-3,5-dibenzylidene-4-piperidones were synthesized using a newly developed "one-pot" synthetic method. Due to the fact that all of them have the same aryl substituents (phenyl or 4-chlorophenyl) in the arylidene moiety, it is possible to compare the relevant contribution of the single-point structural modifications (type of ring or N-substitution) on their potency on the basis of their IC 50 values. Their antiproliferative activity was evaluated against the following four human adherent cancer cell lines: HeLa, A431, A2780, and MCF7. The cytotoxicity screen has revealed that the dibenzylidene dienones in general dominate the monobenzylidene enones in this respect. The nitrogen-containing heterocyclic dienones at the same time displayed higher inhibitory properties toward these human carcinoma cell lines compared with their homocyclic dienone analogs. One of the eight newly prepared 4-piperidone derivatives, N-(γ-oxobutyl)-(E,E)-3,5-bis(p-chlorobenzylidene)-4-piperidone is as potent a cell growth inhibitor (IC 50 of 0.438-1.409 μM) as the N-methyl-(E,E)-3,5-bis(p-chlorobenzylidene)-4-piperidone (IC 50 of 0.447-1.048 μM), one of the most active among the previously described compounds in this series. Catalytic hydrogen-transfer isomerization of compounds with two exocyclic benzylidene double bonds to derivatives with endocyclic double bonds results in the complete loss of antiproliferative activity. The structural modifications and 50 % inhibitory concentration (IC 50) values resulted in correlations which can promote the design of more potent derivatives of the 4-piperidone dienones.

A new stepwise synthesis of a family of propylamines derived from diatom silaffins and their activity in silicification

A new method for the stepwise synthesis of propylamines containing fragments of N-methyl propylamine as found in diatom bioextracts is presented and their activity in silicic acid condensation is described. The Royal Society of Chemistry 2006.