6329-48-2

Basic information

• Product Name: dimethyl [(4-chlorophenyl)(hydroxy)methyl]phosphonate
• CAS NO: 6329-48-2
• Molecular Formula: C₉H₁₂ClO₄P
• Molecular Weight: 250.6159
• Mol File: 6329-48-2.mol
• Article Data: 29

Chemical Properties

• Boiling Point: 370.4°C at 760 mmHg
• Flash Point: 177.8°C
• Density: 1.348g/cm³
• Vapor Pressure: 3.86E-06mmHg at 25°C
• Refractive Index: 1.528
• CAS DataBase Reference: dimethyl [(4-chlorophenyl)(hydroxy)methyl]phosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl [(4-chlorophenyl)(hydroxy)methyl]phosphonate(6329-48-2)
• EPA Substance Registry System: dimethyl [(4-chlorophenyl)(hydroxy)methyl]phosphonate(6329-48-2)

Safety Data

• Hazardous Substances Data: 6329-48-2(Hazardous Substances Data)

Upstream product

• 2033-24-1 cycl-isopropylidene malonate 
• 104-88-1 4-chlorobenzaldehyde 
• 121-45-9 phosphorous acid trimethyl ester 
• 96-36-6 methyl phosphite 
• 36198-87-5 dimethyl trimethylsilyl phosphite 
• 122-01-0 4-chloro-benzoyl chloride 
• 33493-32-2 dimethyl p-chlorobenzoylphosphonate 
• 623-12-1 4-chloromethoxybenzene 
• 868-85-9 Dimethyl phosphite 

Downstream Products

• 845899-03-8 (2,4-dichloro-phenoxy)-acetic acid (4-chloro-phenyl)-(dimethoxy-phosphoryl)-methyl ester 
• 1208065-66-0 dimethyl [(4-chlorophenyl)(6-oxo-6λ5-dibenzo[d,f][1,3,2]dioxaphosphepin-6-yl)ethyl]phosphonate 
• 123989-29-7 1-(p-chlorophenyl)-2-cyclopropyl-2-methylethan-1-one 
• 63694-16-6 1-(4-chlorophenyl)-1-hydroxymethylphosphonic acid 
• 1614827-39-2 O,O-dimethyl 1-((4,6-dichloropyrimidin-2-yl)carbamyloxy)-1-(4-chlorophenyl)methylphosphonate 
• 1352612-24-8 (4-chlorophenyl)(dimethoxyphosphoryl)methyl cinnamate 
• 1332458-74-8 (4-chlorophenyl)(dimethoxyphosphoryl)methyl 2-(4,6-dimethoxypyrimidin-2-yloxy)benzoate 
• 1146599-29-2 O,O-dimethyl 1-[(6-chloropyridin-3-yl)methyl]-5-methyl-1H-1,2,3-triazol-4-ylcarbonyloxy-(4-chlorophenyl)methyl-phosphonate 
• 667462-16-0 chloro-acetic acid (4-chloro-phenyl)-(dimethoxy-phosphoryl)-methyl ester 

Relevant articles and documents

O-allylated pudovik and passerini adducts as versatile scaffolds for product diversification

The palladium-catalyzed O-allylation of α-hydroxyphosphonates and α-hydroxyamides obtained from Pudovik and Passerini multicomponent reactions has allowed interesting and highly straightforward access to a variety of building blocks for product diversific

Biocatalytic Promiscuity of Lipases in Carbon-Phosphorus Bond Formation

A promiscuous lipase-catalyzed carbon-phosphorus bond formation is presented. The developed enzymatic Pudovik-Abramov reaction of various aromatic and aliphatic aldehydes with dialkyl phosphonates provides biologically and pharmacologically relevant α-hyd

Rational synthesis of α-hydroxyphosphonic derivatives including dronic acids

New, green methods have been elaborated for the syntheses of α-hydroxyphosphonates and α-hydroxymethylenebisphosphonic derivatives (HMBPs, dronates). α-Hydroxyphosphonates were prepared via the Pudovik reaction, while the synthesis of HMBPs has been performed in the three-component reaction of carboxylic acids, phosphorus trichloride and phosphorus acid.