6341-07-7

Basic information

• Product Name: 1,3,4,5,6-penta-O-acetylhex-2-ulose
• CAS NO: 6341-07-7
• Molecular Formula: C₁₆H₂₂O₁₁
• Molecular Weight: 390.3393
• Mol File: 6341-07-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 478.1°C at 760 mmHg
• Flash Point: 208°C
• Density: 1.266g/cm³
• Vapor Pressure: 2.65E-09mmHg at 25°C
• Refractive Index: 1.463
• CAS DataBase Reference: 1,3,4,5,6-penta-O-acetylhex-2-ulose(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4,5,6-penta-O-acetylhex-2-ulose(6341-07-7)
• EPA Substance Registry System: 1,3,4,5,6-penta-O-acetylhex-2-ulose(6341-07-7)

Safety Data

• Hazardous Substances Data: 6341-07-7(Hazardous Substances Data)

Usage

General Description

1,3,4,5,6-penta-O-acetylhex-2-ulose is a chemical compound with the molecular formula C14H18O9. It is a derivative of hex-2-ulose and contains five acetyl groups attached to the hexose ring. 1,3,4,5,6-penta-O-acetylhex-2-ulose is commonly used in organic synthesis and serves as a key intermediate in the production of various pharmaceuticals and natural products. It has also been studied for its potential applications in the food and flavor industries. 1,3,4,5,6-penta-O-acetylhex-2-ulose exhibits unique chemical reactivity and is of interest to researchers for its potential synthetic and medicinal uses.

Upstream product

• 57-48-7 D-Fructose 
• 108-24-7 acetic anhydride 
• 506-96-7 Acetyl bromide 
• 5435-44-9 (E)-3-Ureido-but-2-enoic acid ethyl ester 
• 20764-61-8 Penta-O-acetyl-β-D-fructopyranose 
• 64-19-7 acetic acid 
• 56-82-6 Glyceraldehyde 
• 78184-44-8 Penta-O-acetyl-keto-L-fructose 
• 35304-04-2 L-sorbose 1,3,4,5,6-pentaacetate 
• 214490-56-9 peracetylated sorbose 
• 6347-01-9 fructopyranose 
• 55221-54-0 1,3,4,5-Tetra-O-acetyl-β-D-fructopyranose 
• 14214-09-6 3,4,5,6-tetra-O-acetyl-1-deoxy-1-diazo-keto-D-fructose 

Downstream Products

• 6341-07-7 Penta-O-acetyl-keto-DL-fructose 
• 85993-81-3 1,3,4,5,6,-penta-O-acetyl-keto-D-fructose(2,4-dinitrophenyl)hydrazone, Z isomer 
• 85993-79-9 1,3,4,5,6-penta-O-acetyl-keto-D-fructose(2,4-dinitrophenyl)hydrazone, E isomer 
• 54538-26-0 1,3,4,5,6-penta-O-acetyl-keto-D-fructose(2,4-dinitrophenyl)hydrazone 
• 7621-93-4 D-fructose diethyl mercaptal pentaacetate 

Relevant articles and documents

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A derivatization procedure for the simultaneous analysis of iminosugars and other low molecular weight carbohydrates by GC-MS in mulberry (Morus sp.)

Different derivatization procedures were assayed to simultaneously analyse iminosugars such as deoxynojirimycin (DNJ) or fagomine and other carbohydrates of low molecular weight by gas chromatography coupled to mass spectrometry (GC-MS) in Morus sp. Both oximation + trimethylsilylation and oximation + acetylation allowed the separation of target compounds, whereas trimethylsilyl (TMS) and acetylated derivatives showed several coelutions. Nevertheless, oximation + acetylation were discarded for giving inaccurate results for ketoses due to their incomplete derivatization. Different conditions for the conversion into trimethylsilyl oximes (TMSO) were assayed, the best results being achieved using hexamethyldisilazane with trifluoroacetic acid as silylation agent. Contents of iminosugars (DNJ, fagomine and pipecolic acid derivatives) and other carbohydrates such as mono and disaccharides, myo-inositol and galactinol isomers in mulberry extracts (fruits, leaves and branches) were determined by GC-MS using the TMSO procedure.

Acylic sugar derivatives for GC/MS analysis of 13C-enrichment during carbohydrate metabolism

Metabolic profiling with stable-isotope tracers in combination with gas chromatography/mass spectrometry (GC/ MS) is a well-established technique for measuring substrate redistribution within metabolic pathways. This analysis relies on the ability to localize and quantify the fractional incorporation of 13C isotope into each carbon atom of precursor-derived metabolites. In this paper, several carbohydrate derivatization procedures (peracetylation, deuterioalditol acetates, and aldononitrile acetates) are evaluated for the positional isotopic information obtained by gas chromatography/electron impact mass spectrometry (GC/EI-MS). These derivatives have been compared for the quantitative evaluation of 13C distribution into isotopomers of 13C-labeled aldoses and ketoses, and the fragmentation pathways for 15 hexoses, pentoses, and amino sugars of biological origin have been assessed. In addition, a new type of carbohydrate derivative (dialkyldithioacetal acetates) has been developed for GC/MS that retains the charge on the anomeric carbon of the original monosaccharide. Electron impact ionization of these derivatives generates well-resolved base peaks arising from C1-C2 bond cleavage with charge retention at the C1 thiol groups. The dialkyldithioacetal acetates are uniquely well suited for measuring isotopic enrichment into the characteristic anomeric carbon of aldose sugars and will facilitate the global analysis of metabolic flux in carbohydrate pathways.