63452-53-9

Basic information

• Product Name: AcetaMide, N-[(2-Methoxyphenyl)Methyl]-
• Synonyms: AcetaMide, N-[(2-Methoxyphenyl)Methyl]-
• CAS NO: 63452-53-9
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.21572
• Mol File: 63452-53-9.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: AcetaMide, N-[(2-Methoxyphenyl)Methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: AcetaMide, N-[(2-Methoxyphenyl)Methyl]-(63452-53-9)
• EPA Substance Registry System: AcetaMide, N-[(2-Methoxyphenyl)Methyl]-(63452-53-9)

Safety Data

• Hazardous Substances Data: 63452-53-9(Hazardous Substances Data)

Upstream product

• 6850-57-3 2-methoxybenzylamine 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 2033-24-1 cycl-isopropylidene malonate 
• 64-19-7 acetic acid 
• 60-35-5 acetamide 
• 135-02-4 ortho-anisaldehyde 
• 141-78-6 ethyl acetate 
• 6609-56-9 2-methoxy-benzonitrile 

Downstream Products

• 1388628-63-4 3-(N-acetylaminomethyl)-3',4,4',5'-tetramethyloxy-(Z)-stilbene 
• 80311-94-0 N-(2-hydroxybenzyl)acetamide 
• 1448992-65-1 {3-[2-(acetylamino-methyl)-phenoxy]-propyl}-carbamic acid tert-butyl ester 
• 1448992-66-2 tert-butyl-3-(2-(aminomethyl)phenoxy)propylcarbamate 
• 1448992-68-4 [3-(2-isocyanatomethyl-phenoxy)-propyl]-carbamic acid tert-butyl ester 
• 1448992-67-3 [ (2-{3-[2-(3-tert-butoxycarbonylamino-propoxy)-benzyl]-ureido}thiazole-4-carbonyl)-amino]-acetic acid methyl ester 
• 1448992-69-5 [(2-{3-[2-(3-tert-butoxycarbonylamino-propoxy)-benzyl ]-ureido}-thiazole-4-carbonyl)-amino ]-acetic acid 
• 1448992-70-8 methyl-3-(2-(2-(3-(2-(3-(tert-butoxycarbonylamino)propoxy) benzyl)ureido )thiazole-4-carboxamido )acetamido )-3-phenylpropanoate 
• 1448992-73-1 (R)-ethyl-3-(2-(2-(3-(2-(3-(tert-butoxycarbonylamino)propoxy)benzyl)ureido)thiazole-4-carboxamido)acetamido)-3-(pyridin-3-yl)propanoate 
• 1028-96-2 2-(2-methoxyphenyl)quinazolin-4(3H)-one 
• 62924-83-8 N-ethyl-N-[(2methoxyphenyl)methyl]amine 
• 111087-96-8 (S)-2-Amino-3-[4-(3-aminomethyl-4-hydroxy-phenoxy)-3,5-diiodo-phenyl]-propionic acid; hydrobromide 
• 111088-34-7 (S)-2-Acetylamino-3-{4-[3-(acetylamino-methyl)-4-methoxy-phenoxy]-3,5-diiodo-phenyl}-propionic acid ethyl ester 
• 111088-28-9 Bis-[3-(acetylamino-methyl)-4-methoxy-phenyl]-iodonium; iodide 

Relevant articles and documents

Environmentally benign decarboxylative: N-, O-, and S-Acetylations and acylations

An operationally simple and general method for acetylation and acylation of a wide variety of substrates (amines, alcohols, phenols, thiols, and hydrazones) has been reported. Meldrum's acid and its derivatives have been used as an air-stable, non-volatile, cost-effective, and easy to handle acetylating/acylating agent. Easily separable byproducts (CO2 and acetone) allowed the isolation of analytically pure acetylated products without the requirement of work-up and any chromatography. This journal is

Iridium-Catalyzed Benzylamine C-H Alkenylation Enabled by Pentafluorobenzoyl as the Directing Group

The first iridium-catalyzed oxidative alkeynylation of benzylamines with acrylates enabled by a new directing group pentafluorobenzoyl has been developed. The reaction proceeded efficiently in the presence of silver acetate as oxidant and chlorobenzene as

Acetic acid as a catalyst for the N-acylation of amines using esters as the acyl source

We report a cheap and simple method for the acetylation of a variety of amines using catalytic acetic acid and either ethyl acetate or butyl acetate as the acyl source. Catalyst loadings as low as 10 mol% afforded acetamide products in excellent yields at temperatures ranging from 80-120 °C. The methodology can also be successfully applied for the synthesis of a broad range of other amides, including the formation of formamides at 20 °C.