634610-79-0

Basic information

• Product Name: 2-O-benzyl-5-O-(4'-nitrophenyl)-1,4:3,6-dianhydro-D-mannitole
• Synonyms: 2-O-benzyl-5-O-(4'-nitrophenyl)-1,4:3,6-dianhydro-D-mannitole
• CAS NO: 634610-79-0
• Molecular Weight: 357.363
• Mol File: 634610-79-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-O-benzyl-5-O-(4'-nitrophenyl)-1,4:3,6-dianhydro-D-mannitole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-O-benzyl-5-O-(4'-nitrophenyl)-1,4:3,6-dianhydro-D-mannitole(634610-79-0)
• EPA Substance Registry System: 2-O-benzyl-5-O-(4'-nitrophenyl)-1,4:3,6-dianhydro-D-mannitole(634610-79-0)

Safety Data

• Hazardous Substances Data: 634610-79-0(Hazardous Substances Data)

Upstream product

• 350-46-9 4-Fluoronitrobenzene 
• 183624-93-3 (3R,3aR,6R,6aR)-6-benzyloxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-ol 
• 100-39-0 benzyl bromide 
• 641-74-7 1,4:3,6-dianhydro-D-mannitol 

Downstream Products

• 745794-64-3 (3R,3aR,6R,6aR)-3-Benzyloxy-6-(2'-methanesulfonyl-biphenyl-4-yloxy)-hexahydro-furo[3,2-b]furan 
• 745794-66-5 2-O-[4'-(5''-methyl[1,2,4]oxadiazol-3''-yl)phenyl]-5-O-[4'''-(piperidin-2''''-on-1''''-yl)phenyl]-1,4:3,6-dianhydro-D-sorbitole 
• 745794-52-9 2-O-(4'-cyanophenyl)-5-O-[4''-(2'''-tert-butylaminosulfonylphenyl)phenyl]-1,4:3,6-anhydro-D-mannitole 
• 745794-53-0 2-O-(3'-cyanophenyl)-5-O-[4''-(2'''-tert-butylaminosulfonylphenyl)phenyl]-1,4:3,6-anhydro-D-sorbitole 
• 745794-51-8 2-O-(3'-cyanophenyl)-5-O-[4''-(2'''-tert-butylaminosulfonylphenyl)phenyl]-1,4:3,6-anhydro-D-mannitole 
• 745794-65-4 2-O-benzyl-5-O-[4'-(piperidin-2''-on-1''-yl)phenyl]-1,4:3,6-dianhydro-D-mannitole 
• 634610-96-1 2-O-[4'-(5''-methyl[1,2,4]oxadiazol-3''-yl)phenyl]-5-O-[4'''-(2''''-methylsulfonylphenyl)phenyl]-1,4:3,6-dianhydro-D-sorbitole 
• 634610-87-0 2-O-(4'-cyanophenyl)-5-O-[4''-(2'''-tert-butylaminosulfonylphenyl)phenyl]-1,4:3,6-anhydro-D-sorbitole 
• 634610-85-8 2-O-[4'-(2''-tert-butylaminosulfonylphenyl)phenyl]-1,4:3,6-anhydro-D-mannitole 
• 634610-92-7 2-O-benzyl-5-O-[4'-(2''-methylthiophenyl)phenyl]-1,4:3,6-dianhydro-D-mannitole 
• 634610-94-9 2-O-[4'-(2''-methylsulfonylphenyl)phenyl]-1,4:3,6-dianhydro-D-mannitole 
• 634610-81-4 2-O-benzyl-5-O-(4'-iodophenyl)-1,4:3,6-dianhydro-D-mannitole 
• 745794-49-4 4-((3R,3aR,6R,6aR)-6-Benzyloxy-hexahydro-furo[3,2-b]furan-3-yloxy)-phenylamine 

Relevant articles and documents

Synthesis of dianhydrohexitole-based benzamidines as factor xa inhibitors using cross couplings, phenyl ether and amidine formations as key steps

Starting with isosorbide or isomannide several dianhydrohexitole-based benzamidines were synthesized as potential factor Xa inhibitors. The key steps for the synthesis of the bisbenzamidines were nucleophilic aromatic substitutions and Mitsunobu reactions