634610-81-4Relevant articles and documents
Dianhydrohexitole-based benzamidines: An efficient synthesis of new factor Xa inhibitors
Vogler, Marko,Koert, Ulrich,Harms, Klaus,Dorsch, Dieter,Gleitz, Johannes,Raddatz, Peter
, p. 1211 - 1228 (2007/10/03)
Dianhydrohexitole-based benzamidines were synthesised as potential factor Xa inhibitors. The key steps for the synthesis of a bis-benzamidine series were nucleophilic aromatic substitutions and Mitsunobu reactions to introduce substituted phenyl ether moi