6386-80-7

Basic information

• Product Name: benzothiophene-6-carbaldehyde
• Synonyms: benzothiophene-6-carbaldehyde;Benzo[b]thiophene-6-carboxaldehyde;Benzo[b]thiophene-6-carbaldehyde;1-Benzothiophene-6-carbaldehyde
• CAS NO: 6386-80-7
• Molecular Formula: C9H6OS
• Molecular Weight: 162.21
• Mol File: 6386-80-7.mol

Chemical Properties

• Melting Point: 42.0-42.5 °C
• Boiling Point: 303.2°C at 760 mmHg
• Flash Point: 137.2°C
• Appearance: /
• Density: 1.3g/cm³
• Vapor Pressure: 0.000944mmHg at 25°C
• Refractive Index: 1.719
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: benzothiophene-6-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: benzothiophene-6-carbaldehyde(6386-80-7)
• EPA Substance Registry System: benzothiophene-6-carbaldehyde(6386-80-7)

Safety Data

• Hazardous Substances Data: 6386-80-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Benzothiophene-6-carbaldehyde is employed as a key building block in the synthesis of various drugs and bioactive compounds. Its unique chemical structure contributes to the development of novel pharmaceuticals with potential therapeutic applications.
Used in Organic Synthesis:
As a versatile intermediate, benzothiophene-6-carbaldehyde is used in organic synthesis for creating a wide range of chemical compounds. Its reactivity and functional group compatibility make it a valuable component in the production of various organic molecules.
Used in Dye Synthesis:
Benzothiophene-6-carbaldehyde is utilized in the synthesis of dyes due to its ability to form colored compounds. Its incorporation into dye molecules enhances their color properties and contributes to the development of new dye products for various applications.
Used in Pesticide Production:
In the agricultural industry, benzothiophene-6-carbaldehyde is used as a starting material for the production of pesticides. Its chemical properties allow for the creation of effective pest control agents, contributing to improved crop protection and yield.
Used in Fine Chemicals Industry:
Benzothiophene-6-carbaldehyde is also employed in the synthesis of other fine chemicals, such as fragrances, flavorings, and specialty chemicals. Its unique structure and reactivity enable the development of high-quality products for various applications in this industry.

InChI:InChI=1/C9H6OS/c10-6-7-1-2-8-3-4-11-9(8)5-7/h1-6H

Upstream product

• 6179-28-8 benzothiophene-6-methanol 
• 6179-26-6 benzo[b]thiophene-6-carboxylic acid 
• 154650-81-4 benzo[b]thiophene-6-carbonitrile 
• 17347-29-4 1-bromo-3-(2,2-diethoxy-ethylsulfanyl)benzene 
• 6320-01-0 3-Bromothiophenol 
• 17347-32-9 6-bromobenzothiophene 
• 68-12-2 N,N-dimethyl-formamide 
• 2591-86-8 N-Formylpiperidine 
• 106-93-4 ethylene dibromide 
• 16587-47-6 6-methylbenzo[b]thiophene 
• 14315-11-8 4-methylbenzo[b]thiophene 
• 94-36-0 dibenzoyl peroxide 
• 202350-59-2 4,5-dihydrobenzo[b]thiophene-6-carbaldehyde 

Downstream Products

• 6179-26-6 benzo[b]thiophene-6-carboxylic acid 

Relevant articles and documents

SPIRO-OXADIAZOLINE COMPOUNDS AS AGONISTS OF α-7-NICOTINIC ACETYLCHOLINE RECEPTORS

The present invention relates to novel spiro-oxadiazoline compounds that are suitable as agonists or partial agonists of a7-nAChR, and pharmaceutical compositions of the same, methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering a spiro-oxadiazoline cx7-nAChR agonist or partial agonist, to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.

SUBSTITUTED TRIAZOLE AND IMIDAZOLE COMPOUNDS

The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are LMP7 inhibitors and may be useful in treating associated inflammatory diseases and disorders such as, for example, rheumatoid arthritis, lupus and irritable bowel disease.

N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME

An N-alkoxyalkyl-N,N-dialkylamine derivative represented by the following general formula [1]: wherein the ring D represents a 5- or 6-membered heterocyclic ring or hydrocarbon ring; R3 and R4, which are the same or different, represent an unsubstituted or substituted alkyl, cycloalkyl or aralkyl group; and R1, R2, R5, R6, R7, R8, m and n are as defined in the specification, or a salt thereof has an anti-hypoxic activity, a nerve-protecting activity and a nerve regeneration promoting activity and is useful for the treatment of neurodegenerative diseases.

Studies in sulfur heterocycles. Part 12. Use of 5,6-dihydrobenzo[b]-thiophen-7(4H)-one in the synthesis of condensed sulfur heterocycles

Readily available 5,6-dihydrobenzo[b]thiophen-7(4H)-one has been used as a convenient intermediate for the synthesis of several condensed heterocyclic systems and substituted benzo[b]thiophenes.

5-[Substituted bicyclic aryl or heteroaryl]cyclohexane-1,3-dione herbicides

The invention concerns novel compounds of the formula I STR1 wherein: A is selected from CH and N; B is selected from oxygen, sulfur, CH2 and the group N-Z wherein Z is selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, cy