16587-47-6

Basic information

• Product Name: 6-METHYLBENZOTHIOPHENE
• Synonyms: 6-Methyl-1-benzothiophene;6-Methylbenzo[b]thiophene;6-Methylthianaphthene;Benzo[b]thiophene, 6-methyl-;Benzothiophene, 6-methyl;6-METHYLBENZOTHIOPHENE
• CAS NO: 16587-47-6
• Molecular Formula: C₉H₈S
• Molecular Weight: 148.22
• EINECS: 250-609-2
• Mol File: 16587-47-6.mol
• Article Data: 9

Chemical Properties

• Melting Point: 42.0-42.5 °C
• Boiling Point: 243 °C at 760 mmHg
• Flash Point: 72.4 °C
• Appearance: /
• Density: 1.146 g/cm³
• Vapor Pressure: 0.0514mmHg at 25°C
• Refractive Index: 1.652
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 6-METHYLBENZOTHIOPHENE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-METHYLBENZOTHIOPHENE(16587-47-6)
• EPA Substance Registry System: 6-METHYLBENZOTHIOPHENE(16587-47-6)

Safety Data

• Hazardous Substances Data: 16587-47-6(Hazardous Substances Data)

Usage

General Description

6-Methylbenzothiophene is a chemical compound with the molecular formula C9H8S. It is a heterocyclic aromatic compound that contains a benzene ring fused to a thiohene ring with a methyl group attached to the benzene ring. This chemical is commonly used as a building block in the synthesis of various organic compounds and pharmaceutical drugs. It is also known for its role in the composition of crude oil and is often used as a marker for the presence of hydrocarbons in environmental samples. 6-Methylbenzothiophene is considered to be a hazardous substance, as it may cause skin and eye irritation, and is a potential environmental pollutant. Therefore, proper handling and disposal methods should be followed when working with this chemical.

InChI:InChI=1/C9H8S/c1-7-2-3-8-4-5-10-9(8)6-7/h2-6H,1H3

Upstream product

• 86119-84-8 phosphoric acid 
• 51830-51-4 m-tolylsulfanyl-acetaldehyde diethylacetal 
• 68670-98-4 2,3-dihydro-6-methylbenzo[b]thiophen-3-one 
• 17347-32-9 6-bromobenzothiophene 
• 13061-96-6 dihydroxy-methyl-borane 
• 596805-23-1 N,N-diethyl-2-methylsulfanyl-4-methylbenzamide 
• 2728-05-4 N,N-Diethyl-p-toluamid 
• 70260-86-5 4-(S)-oxiranylmethoxy-1H-indole 
• 574706-08-4 1-(1H-indol-4-yloxy)-3-[4-(4-methyl-benzo[b]thiophen-2-yl)-piperidin-1-yl]-propan-2-ol 
• 6007-83-6 2,3-thiophenedicarboxylic acid anhydride 
• 542-92-7 cyclopenta-1,3-diene 
• 3996-30-3 2-[(3-methylphenyl)thio]acetic acid 
• 57860-49-8 3-methyl-1-(2,2-dimethoxy-ethyl-sulfanyl)-benzene 

Downstream Products

• 89816-56-8 2-allyl-6-methylbenzothiophene 
• 22720-97-4 2-(4-methyl)phenyl-6-methylbenzothiophene 
• 22721-01-3 5-methyl-2-p-tolylbenzothiophen 
• 27047-29-6 6-methyl-2-phenylbenzothiophen 
• 82787-72-2 6-methylbenzothiophene-2-carboxylic acid methyl ester 
• 820240-91-3 6-methylbenzothiophene boronic acid 
• 6386-80-7 benzo[b]thiophene-6-carbaldehyde 
• 10133-25-2 benzo[b]thiophene-4-carboxaldehyde 
• 82787-85-7 6-methylbenzothiophene-3-carboxylic acid methyl ester 
• 82787-84-6 6-methylbenzothiophene-3-carboxylic acid 

Relevant articles and documents

Enantioselective hydroarylation or hydroalkenylation of benzo[b]thiophene 1,1-dioxides with organoboranes

An efficient protocol for the asymmetric hydroarylation and hydroalkenylation of benzo[b]thiophene 1,1-dioxides with organoboranes has been developed. The combination of a rhodium(I) precatalyst and a chiral diene ligand constitutes the catalytic system, which enables the facile synthesis of 2,3-dihydrobenzo[b]thiophene 1,1-dioxides in good yields with high enantioselectivities. The merging of this asymmetric hydroarylation with the downstream alkylations delivers 2,3-dihydrobenzo[b]thiophene 1,1-dioxides that contain two continuous quaternary stereocenters with high enantioselectivities in a diastereodivergent manner.

Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 1

A series of 1-aryloxy-3-piperidinylpropan-2-ols possessing potent dual 5-HT1A receptor antagonism and serotonin reuptake inhibition was discovered. 1-(1H-Indol-4-yloxy)-3-(4-benzo[b]thiophen-2-ylpiperidinyl)propan-2-ols exhibited selective and high affinity at the 5-HT1A receptor and serotonin reuptake inhibition at nanomolar concentrations for dual activities.

Evolution of products in the combustion of scrap tires in a horizontal, laboratory scale reactor

A horizontal laboratory reactor was used to study the evolution of byproducts from the combustion of scrap tires at five nominal temperatures (ranging from 650 to 1050 °C) and different oxygen:sample ratios A model was used to calculate the bulk air ratio (λ), and the oxygen consumption was discussed considering this ratio λ. More than 100 volatile and semivolatile compounds were identified and quantified by gas chromatography mass spectrometry, plotting their yields vs the bulk air ratio and temperature. Five different behaviors considering the bulk air ratio and the temperature were identified.